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This case report describes Zoon's vulvitis or plasma cell vulvitis (PCV) with coexisting lichen planus (LP) treated with methotrexate. PCV is a rare, chronic, benign idiopathic inflammatory condition of the vulvar mucosa, characterized by a bright-red, chronic lesion of mucosa. Typically, it presents as atrophic, shiny, red plaques that can affect any part of the vulva and can spread symmetrically and bilaterally with the propensity of chronicity and gradual coalescence.

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Refractory Vulvovaginal Lichen Planus Responding to Oral Tofacitinib.

Australas J Dermatol

December 2024

Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Jodhpur, India.

Erosive vulvovaginal lichen planus is a severe form of Lichen planus (LP) that can result in chronic scarring if not treated. It can cause narrowing of the introitus, resulting in pain, itch, dyspareunia, dysuria, and recurrent urinary tract infections caused by retention of urine. Therefore, an effective and safer therapeutic approach is required.

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Successful Microablative Fractional Carbon Dioxide Laser Therapy for Vulvar Lichen Sclerosus: A Case Report and Mini-review.

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Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan.

Vulvar lichen sclerosus (VLS) is a chronic inflammatory skin disorder affecting the vulvar region. VLS predominantly affects women, and most cases occur after menopause. Common symptoms include itching, skin-whitening, pain, discomfort, fissures, and scarring.

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An Observational Study on Female Genital Dermatoses and the Impact of Chronic Genital Dermatoses on Quality of Life in Adult Females.

Indian J Dermatol

October 2024

From the Department of Dermatology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Background: Female genital dermatoses (FGD) or vulvar dermatoses are a group of disorders that affect the vulva and contiguous parts. Most of the FGDs can be chronic or recurrent. Effects on Quality of life (QoL) in patients having dermatological conditions are well studied but this is not the case in vulvar dermatoses.

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Article Synopsis
  • The study focused on evaluating sexual distress and quality of life in women suffering from moderate-to-severe genital erosive lichen planus (GELP) in Norway.
  • A total of 36 women were assessed using the Female Sexual Distress Scale (FSDS-R) for sexual distress and the Dermatology Life Quality Index (DLQI) for quality of life, with findings showing significant distress and reduced quality of life among many participants.
  • Despite the significant sexual distress and quality of life issues reported, no clear relationships were identified between the severity of the disease and the levels of distress or quality of life, nor was there a correlation with age.
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