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Effectiveness of the primary Bacillus Calmette-Guérin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data.
Lancet Microbe
December 2024
Amsterdam University Medical Centres, Amsterdam, Netherlands; Department of Global Health and Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands.
Background: Tuberculosis vaccine trials using disease as the primary endpoint are large, time consuming, and expensive. An earlier immunological measure of the protection against disease would accelerate tuberculosis vaccine development. We aimed to assess whether the effectiveness of the Bacillus Calmette-Guérin (BCG) vaccine for prevention of Mycobacterium tuberculosis infection was consistent with that for prevention of tuberculosis disease.
View Article and Find Full Text PDFCranial kinesis facilitates quick retraction of stuck woodpecker beaks.
J Exp Biol
March 2022
UMR 7179 C.N.R.S/M.N.H.N., Département Adaptations du Vivant, 57 rue Cuvier, Case Postale 55, 75231 Paris Cedex 05, France.
Much like nails that are hammered into wood, the beaks of woodpeckers regularly get stuck upon impact. A kinematic video analysis of pecking by black woodpeckers shows how they manage to quickly withdraw their beaks, revealing a two-phase pattern: first a few degrees of beak-tip-down rotation about the nasofrontal hinge causes the tip of the upper beak to be retruded while its proximal end is lifted. Next, the head is lifted, causing beak-tip-up rotation about the nasofrontal hinge while the lower beak starts retruding and initiates the final freeing.
View Article and Find Full Text PDFI am just a bill, stuck on Capitol Hill.
JAAPA
March 2019
Johnnie L. Gilpen, Jr., is a 2017 Tillman Scholar, and the Pat Tillman Foundation funded his trip to the Leadership and Advocacy Summit. He is a student in the PA program at the University of Oklahoma Health Sciences Center in Oklahoma City.
A new IOM report seeks to create a new mechanism for collecting and measuring data on public health to give policymakers better tools in steering health policy. Providers hope this doesn't mean they'll be stuck with the bill. "This is a public good and therefore I would not expect that it's reliant on hospital contributions.
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