Although the higher order structure of the Personality Inventory for the (PID-5; Krueger, Derringer, Markon, Watson, & Skodol, 2012), is well-established, the lower order structure and facet-to-domain assignment is inconsistent across studies. Some studies used the five-factor model of adaptive personality (FFM) as a framework to evaluate and characterize this lower order structure; however, findings have been limited in various respects including the use of primarily Caucasian and nonclinical samples. The goal of the current investigation was to clarify and extend knowledge of the lower order structure of the PID-5 through joint PID-5/FFM analysis using an ethnically diverse undergraduate sample ( = 492) and psychiatric patient sample ( = 388). Our findings revealed an optimal five-factor structure in the undergraduate sample (in which Openness facets did not load on any factor) and a six-factor structure in the clinical sample (in which Openness formed its own factor). Domains displayed good convergent validity with the domains of the personality psychopathology five model, except for Disinhibition/Conscientiousness, in which the lack of convergence was explained by Conscientiousness. Furthermore, we evaluated six specific PID-5 facets with respect to interstitiality and optimal PID-5 domain placement, where results supported several recommendations for model modification of the PID-5 structure. These include moving Restricted Affectivity to Detachment from Negative Affectivity, moving Hostility to Antagonism from Negative Affectivity, moving Suspiciousness to Negative Affectivity from Detachment, and removing Submissiveness from the PID-5 measure and the alternative model of personality disorders. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Adv Sci (Weinh)
January 2025
Department of Materials Science & Engineering, Stanford University, Stanford, CA, 94305, USA.
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January 2025
Key Laboratory of Colloid and Interface Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China.
Chirality epitomizes the sophistication of chemistry, representing some of its most remarkable achievements. Yet, the precise synthesis of chiral structures from achiral building blocks remains a profound and enduring challenge in synthetic chemistry and materials science. Here, we demonstrate that achiral colloidal nanocrystals, including Au and Ag nanocrystals, can assemble into long-range-ordered helical assemblies with the assistance of chiral molecules.
View Article and Find Full Text PDFPhys Chem Chem Phys
January 2025
School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia QLD 4072, Australia.
Steroids are organic compounds found in all forms of biological life. Besides their structural roles in cell membranes, steroids act as signalling molecules in various physiological processes and are used to treat inflammatory conditions. It has been hypothesised that in addition to their well-characterised genomic and non-genomic pathways, steroids exert their biological or pharmacological activities an indirect, nonreceptor-mediated membrane mechanism caused by steroid-induced changes to the physicochemical properties of cell membranes.
View Article and Find Full Text PDFPharm Dev Technol
January 2025
Department of Pharmacy, School of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China.
In this paper, the pH-sensitive targeting functional material NGR-poly(2-ethyl-2-oxazoline)-cholesteryl methyl carbonate (NGR-PEtOz-CHMC, NPC) modified quercetin (QUE) liposomes (NPC-QUE-L) was constructed. The structure of NPC was confirmed by infrared spectroscopy (IR) and nuclear magnetic resonance hydrogen spectrum (H-NMR). Pharmacokinetic results showed that the accumulation of QUE in plasma of the NPC-QUE-L group was 1.
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland.
Bone tissue regeneration can be affected by various architectonical features of 3D porous scaffold, for example, pore size and shape, strut size, curvature, or porosity. However, the design of additively manufactured structures studied so far was based on uniform geometrical figures and unit cell structures, which often do not resemble the natural architecture of cancellous bone. Therefore, the aim of this study was to investigate the effect of architectonical features of additively manufactured (aka 3D printed) titanium scaffolds designed based on microtomographic scans of fragments of human femurs of individuals of different ages on in vitro response of human bone-derived mesenchymal stem cells (hMSC).
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