Sample sizes based on three popular indices of risks. | LitMetric

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Sample sizes based on three popular indices of risks. | LitMetric

Sample sizes based on three popular indices of risks.

Hongyue Wang Bokai Wang Xin M Tu Jinyuan Liu Changyong Feng

Gen Psychiatr

Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, USA.

Published: December 2018

Sample size justification is a very crucial part in the design of clinical trials. In this paper, the authors derive a new formula to calculate the sample size for a binary outcome given one of the three popular indices of risk difference. The sample size based on the absolute difference is the fundamental one, which can be easily used to derive sample size given the risk ratio or OR.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371655	PMC
http://dx.doi.org/10.1136/gpsych-2018-100011	DOI Listing

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