The Association between Platelet Distribution Width and Stroke in Atrial Fibrillation Patients.

Ann Clin Lab Sci

Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Hypertension Research Laboratory, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

Published: January 2019

Aims: To explore the association between platelet distribution width (PDW) and stroke in atrial fibrillation (AF) patients.

Methods: This study included 150 AF patients who were divided into stroke and non-stroke groups. Multivariate logistic regression analysis and area under the receiver operating characteristic curve were performed.

Results: Among the 150 patients, 50 and 100 were grouped into the stroke and non-stroke groups, respectively. There were significant differences in systolic blood pressure, total cholesterol, C-reactive protein, and PDW between the groups (<0.05). Multiple logistic regression analysis showed that PDW (OR: 1.56, =0.002) was a risk factor for stroke.

Conclusions: PDW was an important risk factor for stroke in AF patients, suggesting it has the potential to be a new biomarker for predicting stroke.

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