Interleukin-2-inducible T-cell kinase inhibitors modify functional polarization of human peripheral T-cell lymphoma cells.

Blood Adv

Leicester Cancer Research Centre and Ernest and Helen Scott Haematology Research Institute, University of Leicester, Leicester, United Kingdom.

Published: March 2019

ITK inhibitors perturb functional changes due to polarizing culture conditions in normal human tonsil CD4 T cells. Primary human PTCL cells alter their functional properties in culture and ITK inhibitors modify these changes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418494PMC
http://dx.doi.org/10.1182/bloodadvances.2018027821DOI Listing

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