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Validation of a method for estimating pulmonary dead space in ventilated beagles to correct exhaled propofol concentration in mixed air.
BMC Vet Res
January 2025
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Background: Mixed exhaled air has been widely used to determine exhaled propofol concentrations with online analyzers, but changes in dead space proportions may lead to inaccurate assessments of critical drug concentration data. This study proposes a method to correct propofol concentration in mixed air by estimating pulmonary dead space through reconstructing volumetric capnography (Vcap) from time-CO and time-volume curves, validated with vacuum ultraviolet time-of-flight mass spectrometry (VUV-TOF MS).
Methods: Existing monitoring parameters, including time-volume and time-CO curves, were used to determine Vcap.
Venous Air Embolism During Lumbar Spine Surgery Leading to Cardiac Arrest Requiring Prone Chest Compressions: A Case Report.
JBJS Case Connect
October 2024
Department of Orthopaedic Surgery, Brown University, Providence, Rhode Island.
Article Synopsis
- * Prone chest compressions were performed immediately during the surgery, allowing the patient to survive without any postoperative issues.
- * The incident highlights the challenges of treating cardiac arrest due to a venous air embolism (VAE) in spinal surgery and suggests that prone chest compressions may be more effective than waiting to switch to supine positioning for CPR.
Accelerating the Diagnosis of Pandemic Infection Based on Rapid Sampling Algorithm for Fast-Response Breath Gas Analyzers.
Sensors (Basel)
September 2024
Institute of Optoelectronics, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw, Poland.
Article Synopsis
- This paper introduces a novel technique for accurately extracting the alveolar portion of human breath, which is essential for medical diagnostics that analyze the breath for disease screening.
- The alveolar air contains specific concentrations of volatile organic compounds (EVOC) that reflect a person's health; therefore, precise sampling is critical because inaccurate samples can significantly alter diagnostic outcomes.
- The new method utilizes a non-dispersive infrared (NDIR) sensor to monitor carbon dioxide levels, allowing for precise identification of exhalation phases with a minimal uncertainty of just 20 milliseconds, ensuring effective diagnostics can be conducted.
Advanced Critical Care Techniques in the Field.
Crit Care Clin
July 2024
Department of Anesthesiology, University of Maryland School of Medicine, 22 S Greene Street, S11C16, Baltimore, MD 21201, USA. Electronic address:
Critical care principles and techniques continue to hold promise for improving patient outcomes in time-dependent diseases encountered by emergency medical services such as cardiac arrest, acute ischemic stroke, and hemorrhagic shock. In this review, the authors discuss several current and evolving advanced critical care modalities, including extracorporeal cardiopulmonary resuscitation, resuscitative endovascular occlusion of the aorta, prehospital thrombolytics for acute ischemic stroke, and low-titer group O whole blood for trauma patients. Two important critical care monitoring technologies-capnography and ultrasound-are also briefly discussed.
View Article and Find Full Text PDFIs chest tube capnography effective in differentiating between true and false air leaks after minimally invasive thoracic surgery?
Gen Thorac Cardiovasc Surg
November 2024
Division of Thoracic Surgery, Department of Cardiothoracic Surgery and Vascular Sciences, Padua University Hospital, University of Padua, Padua, Italy.
Article Synopsis
- Air leak (AL) is a common complication after thoracic surgery, and this study aimed to develop a method for detecting AL by measuring carbon dioxide (CO) levels in chest drainage.
- In a study involving 104 patients who had video-assisted thoracoscopic surgery (VATS), those with AL showed significantly higher intrapleural CO levels on the first post-operative day.
- The findings suggest that intrapleural CO levels can help assess the risk of AL, indicating a need for further research to establish a standardized CO cutoff for managing chest drainage.
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