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Management of Significant Polyp and Early Colorectal Cancer Is Optimized by Implementation of a Dedicated Multidisciplinary Team Meeting: Lessons Learned From the United Kingdom National Program.
Dis Colon Rectum
May 2022
Rectal Cancer Unit, Basingstoke and North Hampshire Hospital, Basingstoke, United Kingdom.
Background: The concept of significant polyps and early colorectal cancer encompasses complex polyps not amenable to routine snare polypectomy or where malignancy cannot be excluded. The assessment and management of these lesions is contentious and increasingly important due to the significant risk of over- or undertreatment.
Objective: Following the recommendations of the Significant Polyps and Early Colorectal Cancer National Program, we implemented a dedicated multidisciplinary team meeting and analyzed the influence on patient outcomes.
The SPECC national development programme.
Colorectal Dis
March 2019
The Pelican Cancer Foundation, Colorectal Research, Basingstoke, UK.
SPECC: concept, clinical relevance and application.
Colorectal Dis
March 2019
Basingstoke Hospital at Hampshire Hospitals Foundation Trust, Aldermaston Road, Basingstoke, RG24 9NA, Basingstoke, UK.
Hierarchical Y-SNP assay to study the hidden diversity and phylogenetic relationship of native populations in South America.
Forensic Sci Int Genet
March 2011
Department of Forensic Genetics, Institute of Legal Medicine and Forensic Sciences, Charité-Universitätsmedizin Berlin, Germany.
Studying the Y chromosomes of indigenous tribes of Ecuador revealed a lack of strategic SNP assays to examine the substructure of South American native populations. In most studies dealing with South American samples so far only the most common Y-SNP M3 of haplogroup Q was analyzed, because this is known to define a founder group in South America. Studies of SNPs ancestral to Q-M3 (Q1a3a) to confirm the results or the typing of Q subclades have often been neglected.
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