Perifolliculitis capitis abscedens et suffodiens successfully treated with Saireito.

J Dermatol

Department of Dermatology, Meiwa Hospital, Nishinomiya, Japan.

Published: August 2019

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http://dx.doi.org/10.1111/1346-8138.14832DOI Listing

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Article Synopsis
  • Perifolliculitis capitis abscedens et suffodiens (dissecting cellulitis of the scalp) is a rare, chronic condition that affects hair follicles on the scalp and can significantly impact a person’s quality of life.
  • Treatment options are diverse and often challenging to navigate.
  • A case study of a 19-year-old male showed positive results from a combination of surgery and photodynamic therapy, particularly for those who did not respond well to traditional treatments.
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Article Synopsis
  • Dissecting cellulitis of the scalp (DCS) negatively affects patients' physical well-being and body image, and conventional treatments often fail, prompting the exploration of alternative therapies like 5-aminolevulinic acid photodynamic therapy (ALA-PDT).
  • The study involved 12 male patients treated with ALA-PDT, with results assessed through symptom scores and photographic comparisons taken before and after the treatment, focusing on pain relief and recurrence rates.
  • Results indicated that 75% of patients experienced significant reductions in symptoms, with notable improvements in pain relief, subcutaneous sinus tract symptoms, and alopecia, along with a decrease in inflammatory cells in the lesions.
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Photodynamic therapy combined with carbon dioxide laser pretreatment for treatment of perifolliculitis capitis abscedens et suffodiens: A case report.

Photodiagnosis Photodyn Ther

April 2024

Department of Dermatology, Huadong Hospital, Fudan University, 221 West Yan'an Road, Shanghai 200040, China. Electronic address:

Article Synopsis
  • Perifolliculitis capitis abscedens et suffodiens (PCAS) is a tough-to-treat chronic skin condition on the scalp that negatively impacts patients' appearance and quality of life.
  • This study discusses a patient with PCAS who underwent a new treatment combining 20% 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and carbon dioxide (CO2) laser pretreatment.
  • Remarkably, the patient's skin lesions completely cleared within two months, with no recurrence reported after one year, marking a potential breakthrough treatment for PCAS.
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