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Burden of disease and economic impact of human Streptococcus suis infection in Viet Nam. | LitMetric

AI Article Synopsis

  • Streptococcus suis is a zoonotic disease primarily affecting middle-aged men, leading to serious health issues like hearing loss and even death, highlighting the need for attention on its impact in Vietnam.
  • Using surveillance data from 2011-2014, researchers estimated the disease incidence, disability-adjusted life years (DALYs), and economic costs of the infection, providing a comprehensive view from the patient's perspective.
  • The findings revealed significant annual incidence rates and DALYs lost, with direct costs ranging from $370,000 to $500,000 and indirect costs estimated between $2.27 to $2.88 million, indicating a considerable burden on both health and economy.

Article Abstract

Background: Streptococcus suis is a zoonotic disease mainly affecting men of working age and can result in death or long-term sequelae, including severe hearing loss and vestibular dysfunction. We aimed to quantify the burden of disease and economic impact of this infection in Viet Nam.

Methods: The annual disease incidence for the period 2011-2014 was estimated based on surveillance data using a multiple imputation approach. We calculated disease burden in disability-adjusted life years (DALYs) and economic costs using an incidence-based approach from a patient's perspective and including direct and indirect impacts of S. suis infection and its long-term sequelae.

Results: The estimated annual incidence rate was 0.318, 0.324, 0.255 and 0.249 cases per 100 000 population in 2011, 2012, 2013 and 2014, respectively. The corresponding DALYs lost were 1832, 1866, 1467 and 1437. The mean direct cost per episode was US$1635 (95% confidence interval 1352-1923). The annual direct cost was US$370 000-500 000 and the indirect cost was US$2.27-2.88 million in this time period.

Conclusions: This study showed a large disease burden and high economic impact of S. suis infection and provides important data for disease monitoring and control.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580695PMC
http://dx.doi.org/10.1093/trstmh/trz004DOI Listing

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