Objective: There is no standard method for assessing symptoms of the prodrome to bipolar disorder (BD), which has limited progress toward early identification and intervention. We aimed to validate the Bipolar Prodrome Symptom Scale-Abbreviated Screen for Patients (BPSS-AS-P), a brief self-report derived from the validated, clinician-rated Bipolar Prodrome Symptom Interview and Scale-Full Prospective (BPSS-FP), as a means to screen and identify people for whom further evaluation is indicated.
Method: Altogether, 134 participants (aged 12-18 years) were drawn from a study of the pre-syndromal stage of mood and psychotic disorders. All participants had chart diagnoses of a mood- or psychosis-spectrum disorder. Participants were interviewed with the BPSS-FP and completed measures of mania and non-mood psychopathology. Prior to being interviewed, patients completed the BPSS-AS-P. Scores on the BPSS-AS-P were determined by summing the severity and frequency ratings for each item.
Results: BPSS-AS-P scores were highly reliable (Cronbach's alpha = 0.94) and correlated with the interview-based BPSS-FP Mania Symptom Index (r = 0.55, p < .0001). BPSS-AS-P scores had good convergent validity, correlating with the General Behavior Inventory-10M (r = 0.65, p < .0001) and Young Mania Rating Scale; r = 0.48, p < .0001). The BPSS-AS-P had good discriminant validity, not being correlated with scales measuring positive and negative symptoms of psychotic disorders (p-values = 0.072-0.667).
Limitations: Findings are limited by the cross-sectional nature of the study by the fact that the participants were all treatment-seeking. Future studies need to evaluate the predictive validity of the BPSS-AS-P for identifying those who develop BD in a community sample.
Conclusion: BPSS-AS-P has promise as a screening tool for people at risk for BD. Adopting the BPSS-AS-P would support the goal of characterizing the prodrome systematically in order to facilitate research and clinical care.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jad.2019.02.040 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Editorial: Tales from across the psychosis spectrum: understanding differences and similarities in mechanisms and experiences.
Front Psychiatry
November 2024
Douglas Research Center, Montreal, QC, Canada.
State and trait markers to define the continuum of affective disorders.
J Affect Disord
November 2024
Department of Psychiatry and Medical Psychology and Research Institute, Research and Innovation Program for the Development of MU-PLOVDIV (SRIPD-MUP), Creation of a Network of Research Higher Schools, National Plan for Recovery and Sustainability, European Union (NextGenerationEU), Medical University Plovdiv, Vassil Aprilov str. 15a, 4002 Plovdiv, Bulgaria. Electronic address:
Article Synopsis
- - Recent research has gathered extensive biological evidence from various fields like biochemistry and neuroimaging to support the idea of a continuum of affective disorders.
- - This continuum includes two dimensions: a clinical one that ranges from major depressive disorder to the bipolar spectrum, and a causal one focusing on the various underlying factors of these mood disorders.
- - The upcoming Special Issue aims to investigate the complex markers that characterize these affective disorders from both clinical and causal viewpoints.
Validation and psychometric properties of the bipolar prodrome symptom interview and scale-full prospective Chinese version to assess individuals at risk for bipolar disorder.
J Affect Disord
February 2025
The Zucker Hillside Hospital, Department of Psychiatry, Northwell Health, Glen Oaks, NY, USA; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Department of Psychiatry and Molecular Medicine, Hempstead, NY, USA; Charité - Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany; German Center for Mental Health (DZPG), partner site Berlin, Germany.
Background: Bipolar disorder (BD) is a chronic, severe mental illness with a significant socio-economic burden. The early recognition of BD requires reliable and valid instruments.
Objective: We evaluated the psychometric attributes of the Bipolar Prodrome Symptom Interview and Scale-Full Prospective (BPSS-FP)-Chinese version.
Prodromal symptoms of a first manic episode: a qualitative study to the perspectives of patients with bipolar disorder and their caregivers'.
Int J Bipolar Disord
November 2024
Department Bipolar Disorders, Altrecht Institute for Mental Health Care, Lange Nieuwstraat 119, Utrecht, 3512 PG, The Netherlands.
Background: Diagnosing bipolar disorder (BD) is challenging, and adequate treatment is of major importance to minimalize the consequences of the illness. Early recognition is one way to address this. Although in clinical research the prodromal phase of BD is gaining interest, the perspective of patients with BD and their caregivers on prodromal symptoms is still lacking.
View Article and Find Full Text PDFClinical, neurocognitive, neurobiological and functional correlates of sleep difficulties in individuals at-risk for psychosis and mania: A scoping review.
Psychiatry Res
December 2024
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; New York MIRECC, The James J. Peters VA Medical Center, VISN 2, Bronx, NY, USA. Electronic address:
Sleep difficulties are highly prevalent among individuals with schizophrenia and bipolar disorder (BD), playing key roles in the onset, clinical presentation, and course of psychotic and manic episodes. However, less is known about sleep difficulties and their sequelae among individuals at-risk for psychosis and mania. Therefore, we conducted a scoping review of sleep disturbances among individuals at-risk for psychosis or mania.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!