We report on the first case of a periprosthetic joint infection with the anaerobic Gram-positive rod Slackia exigua as the causative agent. The bacterium is part of human oral microbiota and has so far mainly been associated with periodontal diseases.
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http://dx.doi.org/10.1016/j.anaerobe.2019.02.015 | DOI Listing |
J Endod
October 2024
Division of Endodontics, Department of Advanced Oral Sciences and Therapeutics, University of Maryland, School of Dentistry, Baltimore, Maryland. Electronic address:
Introduction: This study characterized the bacteriome in primary endodontic infection (PEI) with apical periodontitis (AP), identified core and rare bacteriome species and community diversity metrics, and analyzed the relationship between the bacteriome composition, diversity and features, and patient variables.
Methods: Twenty-seven patients with PEI and AP were sampled. The DNA was extracted and quantified using quantitative polymerase chain reaction.
IDCases
June 2024
Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India.
Intra-abdominal infections (IAI) are surgical emergencies ranging from appendicitis to peritonitis and intrahepatic infections Anaerobic bacteria including spp. and spp. cause 30-50 % of these infections () is an obligate anaerobe part of the human oral microbiota and has been associated with periodontal problems In this report, we describe a rare occurrence of polymicrobial infection with four anaerobes including in a patient with peritonitis caused by a hidden ileal perforation.
View Article and Find Full Text PDFPrzegl Epidemiol
June 2024
Department of Medical Microbiology, Medical University of Warsaw Katedra i Zakład Mikrobiologii Lekarskiej, Warszawski Uniwersytet Medyczny.
Slackia exigua, originally classified as Eubacterium exiguum, is a Gram-positive, asaccharolytic, rod-shaped anaerobic bacterium. The virulence factors of S. exigua have not been accurately identified.
View Article and Find Full Text PDFOrphanet J Rare Dis
April 2024
Department of Oral and Maxillofacial Diseases, Helsinki University Hospital Head and Neck Center, University of Helsinki, Haartmaninkatu 1, Helsinki, Finland.
Background: Cartilage-hair hypoplasia (CHH) is a rare syndromic immunodeficiency with metaphyseal chondrodysplasia and increased risk of malignancy. In this cross-sectional observational study, we examined HPV status and oral microbiome in individuals with CHH. Oral brush samples were collected from 20 individuals with CHH (aged 5-59 years) and 41 controls (1-69 years).
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2023
Department of Odontology, Umeå University, Umeå, Sweden.
Introduction: Bacterial persistence is considered one of the main causal factors for regenerative endodontic treatment (RET) failure in immature permanent teeth. This interference is claimed to be caused by the interaction of bacteria that reside in the root canal with the stem cells that are one of the essentials for RET. The aim of the study was to investigate whether prolonged exposure of stem cells from the apical papilla (SCAP) to bacterial remnants of Fusobacterium nucleatum, Actinomyces gerensceriae, Slackia exigua, Enterococcus faecalis, Peptostreptococcaceae yurii, commonly found in infected traumatized root canals, and the probiotic bacteria Lactobacillus gasseri and Limosilactobacillus reuteri, can alter SCAP's inflammatory response and mineralization potential.
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