AI Article Synopsis
- - Costello syndrome is a rare genetic disorder causing growth and mental delays, along with unique facial features, and often leads to heart issues, skin growths, and a higher risk of cancers.
- - Anesthetizing patients with Costello syndrome can be challenging due to their anatomical differences and heart conditions, particularly when managing their airways and cardiac health.
- - Most research has focused on children with Costello syndrome regarding anesthesia; however, it’s crucial to assess and prepare for potential adult-specific health issues to ensure safe anesthesia in adults with this condition.
Article Abstract
Costello syndrome is a rare genetic disorder characterized by mental and growth retardation and distinctive coarse facies. A significant proportion of patients with Costello syndrome have hypertrophic cardiomyopathy, papillomata, and malignant tumors. General anesthesia practice, especially airway and cardiac management, in patients with Costello syndrome may be complicated by anatomical features and cardiac abnormalities. There have been several reports on the anesthetic management of children with Costello syndrome, but few have reported on the anesthetic management of adults with Costello syndrome. In adults, careful preoperative evaluation as well as preparation for adult-onset and previously unrecognized medical conditions are key for safe anesthetic management.
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| http://dx.doi.org/10.1213/XAA.0000000000000983 | DOI Listing |
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