Objective: This study aimed to estimate the prevalence of different modes of marijuana consumption (e.g., smoking, ingesting) overall and by sociodemographic factors, marijuana-related perceptions, and other substance use among adolescents, as well as to characterize differences in the usual mode of consumption before and after the initiation of retail marijuana sales in 2014.
Method: Data are from the 2013 and 2015 administrations of the Healthy Kids Colorado Survey, a cross-sectional, school-based survey. We included 9th-12th grade students who reported past-30-day marijuana use in 2013 (n = 2,792; 44.8% female) or 2015 (n = 1,664; 48.9% female). We estimated the prevalence of any past-month use of each mode in 2015 and usual mode of consumption the past month in both years. We tested differences by year, sociodemographics, marijuana-related perceptions, and other substance use using Rao-Scott chi-square tests and multivariable logistic regression.
Results: The prevalence of past-month marijuana use was 20.7% in both years. In 2015, 39.8% of students reported using multiple modes in the past month. Use of any mode other than smoking and use of multiple modes differed by sociodemographics, marijuana-related perceptions, and other substance use. Smoking remained the most common usual mode in 2015. The prevalence of usually ingesting significantly decreased from 4.7% to 2.1% between years, whereas "other mode(s)" significantly increased from 4.0% to 6.0%.
Conclusions: The use of multiple modes of marijuana consumption was prevalent among adolescents in Colorado. The usual mode of consumption changed in years before and after the implementation of retail marijuana sales, suggesting the need for continued surveillance.
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http://dx.doi.org/10.15288/jsad.2019.80.46 | DOI Listing |
J Med Internet Res
January 2025
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: Lifestyle interventions have been acknowledged as effective strategies for preventing type 2 diabetes mellitus (T2DM). However, the accessibility of conventional face-to-face interventions is often limited. Digital health intervention has been suggested as a potential solution to overcome the limitation.
View Article and Find Full Text PDFTrends Pharmacol Sci
January 2025
Department of Anesthesiology and Washington University Pain Center, Washington University School of Medicine, St Louis, MO, USA; Center for Clinical Pharmacology, Washington University School of Medicine, St Louis, MO, USA. Electronic address:
Activation of the μ opioid receptor (MOR) can give analgesia, but also has dangerous side effects. Drugs that target MOR through an allosteric site, meaning they bind outside of the usual pocket, present a novel mode of receptor activation with different pharmacology relative to orthosteric drugs. Recent structural studies give valuable new information on how allosteric modulators interact with MOR.
View Article and Find Full Text PDFObstet Gynecol Surv
December 2024
Professor, Obstetrics and Gynecology, University of Arkansas for the Medical Sciences, Little Rock, AR; Professor, Obstetrics and Gynecology, Virginia Tech Carilion School of Medicine, Roanoke, VA.
Importance: Upper gastrointestinal cancers such as gastric and esophageal cancers are rare malignancies with poor prognosis because it is usually diagnosed in latter stages. Presenting symptoms are frequently presumed pregnancy related rather than malignancy related. This review will raise awareness to consider these aggressive cancers in evaluating gastrointestinal complaints during pregnancy.
View Article and Find Full Text PDFJMIR Form Res
January 2025
Scientific Research, SleepScore Labs, 2175 Salk Avenue, Suite 150, Carlsbad, CA, 92008, United States, 1 858-299-8995.
Background: Insufficient sleep is a problem affecting millions. Poor sleep can trigger or worsen anxiety; conversely, anxiety can lead to or exacerbate poor sleep. Advances in innovative consumer products designed to promote relaxation and support healthy sleep are emerging, and their effectiveness can be evaluated accurately using sleep measurement technologies in the home environment.
View Article and Find Full Text PDFBDJ Open
December 2024
Consultant in Special Care Dentistry, Surrey and Sussex NHS Health Care Trust, Redhill, UK.
Background: Dental treatment may not be possible for patients with a profound acquired brain injury without pharmacological support. Intravenous (IV) sedation with midazolam is a widely accepted, safe, and effective mode of treatment for people with a disability, but there is limited evidence in this patient cohort.
Aims: This evaluation aimed to review the IV sedation service for patients with profound acquired brain injury within the dental department at the Royal Hospital for Neuro-disability.
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