AI Article Synopsis
- Major depressive disorder (MDD) is a significant public health issue worldwide, yet its causes are still not fully understood.
- Fibroblast growth factors (FGFs) play a crucial role in brain development and maintenance, and recent research suggests a link between FGFs and depression.
- The FGF system may serve as potential biomarkers for diagnosing MDD and could lead to new treatment options for the disorder.
Article Abstract
Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood. Fibroblast growth factors (FGFs) belong to a large family of growth factors that are involved in brain development during early periods as well as maintenance and repair throughout adulthood. In recent years, studies have found a correlation between the members of the FGF system and depression. These signaling molecules may be expected to be biomarkers for the diagnosis and prognosis of MDD, and may provide new drug targets for the treatment of depression. Here, we reviewed the correlation between some members of the FGF system and depression.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370647 | PMC |
| http://dx.doi.org/10.3389/fphar.2019.00060 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!