We evaluated markers of sulfadoxine-pyrimethamine (SP) resistance in among 254 returned migrant workers in China from Africa from 2013 to 2016. High prevalences of (97.2%) and (96.5%) mutations were observed. The partially resistant genotype was homogeneously distributed in Africa with a modestly high prevalence (48%), whereas the super resistant genotype was only found in West Africa with a very low frequency (1.2%). The findings provided baseline data about the molecular markers of SP resistance.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496059PMC
http://dx.doi.org/10.1128/AAC.01927-18DOI Listing

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