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Atopic dermatitis (AD), a common chronic inflammatory skin disorder is characterized by a complex pathology with skin-barrier abnormalities, immune dysregulation, and microbial dysbiosis. Patients' quality of life is often negatively impacted by persistent pruritus, sleep disturbance, and recurrent skin infections. In addition, patients may have comorbid atopic as well as nonatopic diseases.
View Article and Find Full Text PDFInsecticide-treated bednets and chemoprophylaxis reduce malaria mortality and parasite prevalence.
Trans R Soc Trop Med Hyg
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Mahidol-Oxford Topical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, 10400.
This commentary discusses an influential study from 1993 that demonstrated, among West African children, an overall mortality benefit of insecticide-impregnated bednets, and the reduction of malaria prevalence by chemoprophylaxis. Led by Brian Greenwood and colleagues in The Gambia, the trial also showed these tools to be affordable and practicable. In the years since, >2 billion bednets have been provided to high-risk populations and have contributed greatly to reductions in malaria-attributable mortality.
View Article and Find Full Text PDFSpotlight commentary: Safety and sustainability of eye drops-More than meets the eye.
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Department of Ophthalmology, University Hospital Centre Zagreb, Zagreb, Croatia.
Inhaled Analgesia in Dermatologic Settings: A Comprehensive Overview of Methoxyflurane.
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Division of Dermatology, University of Calgary, Calgary, AB, Canada.
Pain management is an important aspect of dermatologic procedures, which are typically performed on awake patients in outpatient settings. The first-line modalities for procedural analgesia during most dermatologic procedures are topical and injectable local anesthetics, such as lidocaine. However, in some medical and cosmetic dermatologic procedures, pain cannot be effectively managed with local anesthetics due to procedure-specific lack of efficacy, large treatment surface areas, high dosage requirements, allergies, or other contraindications.
View Article and Find Full Text PDFMHRA - topical steroids.
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Retired academic (art and design education). Email:
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