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Recurrent Miller-Fisher syndrome overlapping Guillain-Barrè syndrome and Bickerstaff brainstem encephalitis: A case report.
Clin Neurol Neurosurg
July 2021
Division of Neurology, Vito Fazzi Hospital, Lecce, Italy.
Miller-Fisher syndrome (MFS) together with Guillan-Barré syndrome (GBS) and Bickerstaff brainstem encephalitis (BBE) are considered to form a continuous clinical spectrum of the same disease, possibly affecting the peripheral and/or central nervous systems, with monophasic symptoms. The frequency of overlapping clinical signs and the risk of recurrence are independent and very low, but no cases of GQ1b-seropositive recurrent MFS overlapping with GBS and BBE have been described so far. Here, we describe for the first time an atypical case of recurrent GQ1b-seropositive MFS overlapping GBS and BBE, 12 years after a previous GQ1b-seronegative typical MFS episode.
View Article and Find Full Text PDFAtaxia and ophthalmoplegia: an atypical case of Miller Fisher syndrome (MFS) with anti-GAD antibody.
Int J Neurosci
October 2022
Department of Neurology, University of Texas Medical Branch, Galveston, TX, USA.
Background: Miller Fisher syndrome (MFS) is frequently encountered variant of Gillian Barre Syndrome (GBS). It has distinct clinical and serological features. Here we describe an atypical GQ1b seronegative case with significantly elevated anti-glutamic acid decarboxylase antibody (GAD-Ab).
View Article and Find Full Text PDFGQ1b-Seronegative Miller Fisher Syndrome Associated With Pembrolizumab.
J Neuroophthalmol
September 2019
Department of Neurology and Ophthalmology (KEG, JHW, and DIK), Michigan State University, East Lansing, Michigan; and Michigan State University College of Osteopathic Medicine (AML), East Lansing, Michigan.
Anti-ganglioside complex antibody profiles in a recurrent complicated case of GQ1b-seronegative miller fisher syndrome and Bickerstaff brainstem encephalitis: a case report.
BMC Neurol
May 2018
Department of Neurology, National Hospital Organization Nagoya Medical Center, 4-1-1 Sannomaru, Naka-ku, Nagoya, Japan.
Background: Guillain-Barré syndrome (GBS), Miller Fisher syndrome (MFS) and Bickerstaff brainstem encephalitis (BBE) are a group of autoimmune neurological disorders (GBS spectrum disorder) that rarely recur. Recently, anti-ganglioside complex antibodies (GSC-Abs) were identified in patients with GBS spectrum disorder. However, there has been no case report describing GSC-Abs profiles in a recurrent case showing different phenotypes.
View Article and Find Full Text PDF[A New Aspect of Anti-Glycolipid Antibodies in Guillain-Barré Syndrome: Ca-Dependent Antibody in Fisher Syndrome-Related Disorders].
Brain Nerve
April 2018
Department of Neurrology, School of Medicine, Kyorin University.
Anti-glycolipid antibodies are key to revealing the pathomechanisms of Guillain-Barré syndrome (GBS). There are correlations between the antigen specificities of the antibodies, clinical features, and preceding infectious agents. It has also been found that some glycoantigens are localized in human peripheral nervous tissues, corresponding to the clinical features.
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