In this paper, we propose the application of time-domain near-infrared spectroscopy to the assessment of oscillations in cerebral hemodynamics. These oscillations were observed in the statistical moments of the distributions of time of flight of photons (DTOFs) measured on the head. We analyzed the zeroth and second centralized moments of DTOFs (total number of photons and variance) to obtain their spectra to provide parameters for the frequency components of microcirculation, which differ between the extracerebral and intracerebral layers of the head. Analysis of these moments revealed statistically significant differences between a control group of healthy subjects and a group of patients with severe neurovascular disorders, which is a promising result for the assessment of cerebral microcirculation and cerebral autoregulation mechanisms.
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http://dx.doi.org/10.1364/BOE.10.000761 | DOI Listing |
Prog Neurobiol
January 2025
Department of Biomedicine, University of Basel, Klingelbergstrasse 50, 4056 Basel, Switzerland. Electronic address:
The brain faces the challenging task of preserving a consistent portrayal of the external world in the face of disruptive sensory inputs. What alterations occur in sensory representation amidst noise, and how does brain activity adapt to it? Although it has previously been shown that background white noise (WN) decreases responses to salient sounds, a mechanistic understanding of the brain processes responsible for such changes is lacking. We investigated the effect of background WN on neuronal spiking activity, membrane potential, and network oscillations in the mouse central auditory system.
View Article and Find Full Text PDFJ Clin Med
January 2025
Faculty of Physical Culture and Health, Institute of Physical Culture Sciences, University of Szczecin, Al. Piastów 40B blok 6, 71-065 Szczecin, Poland.
Amyotrophic lateral sclerosis (ALS) is a complex, progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain, brainstem, and spinal cord. Several neuroimaging techniques can help reveal the pathophysiology of ALS. One of these is the electroencephalogram (EEG), a noninvasive and relatively inexpensive tool for examining electrical activity of the brain with excellent temporal precision.
View Article and Find Full Text PDFBiology (Basel)
January 2025
School of Instrumentation Science and Optoelectronic Engineering, Beihang University, Beijing 100191, China.
Neural oscillations observed during semantic processing embody the function of brain language processing. Precise parameterization of the differences in these oscillations across various semantics from a time-frequency perspective is pivotal for elucidating the mechanisms of brain language processing. The superlet transform and cluster depth test were used to compute the time-frequency representation of oscillatory difference (ODTFR) between neural activities recorded by optically pumped magnetometer-based magnetoencephalography (OPM-MEG) during processing congruent and incongruent Chinese semantics.
View Article and Find Full Text PDFEur J Neurosci
January 2025
Department of Psychology, University of Lübeck, Lübeck, Germany.
Distraction is ubiquitous in human environments. Distracting input is often predictable, but we do not understand when or how humans can exploit this predictability. Here, we ask whether predictable distractors are able to reduce uncertainty in updating the internal predictive model.
View Article and Find Full Text PDFBrain Sci
December 2024
Department of Education, "Roma Tre" University, 00185 Rome, Italy.
Background: The human sensorimotor system can naturally synchronize with environmental rhythms, such as light pulses or sound beats. Several studies showed that different styles and tempos of music, or other rhythmic stimuli, have an impact on physiological rhythms, including electrocortical brain activity, heart rate, and motor coordination. Such synchronization, also known as the "entrainment effect", has been identified as a crucial mechanism impacting cognitive, motor, and affective functioning.
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