A facile one-step hydrothermal synthesis approach was proposed to prepare nitrogen and chlorine co-doped carbon dots (CDs) using l-ornithine hydrochloride as the sole precursor. The configuration and component of CDs were characterized by transmission electron microscopy and X-ray photoelectron and Fourier transform infrared spectroscopies. The obtained CDs (Orn-CDs) with a mean diameter of 2.1 nm were well monodispersed in aqueous solutions. The as-prepared CDs exhibited a bright blue fluorescence with a high yield of 60%, good photostability and low cytotoxicity. The emission of Orn-CDs could be selectively and effectively suppressed by Fe. Thus, a quantitative assay of Fe was realized by this nanoprobe with a detection limit of 95.6 nmol l in the range of 0.3-50 µmol l. Furthermore, ascorbic acid could recover the fluorescence of Orn-CDs suppressed by Fe, owing to the transformation of Fe to Fe by ascorbic acid. The limit of detection for ascorbic acid was 137 nmol l in the range of 0.5-10 µmol l. In addition, the established method was successfully applied for Fe and ascorbic acid sensing in human serum and urine specimens and for imaging of Fe in living cells. Orn-CD-based sensing platform showed its potential to be used for biomedicine-related study because it is cost-effective, easily scalable and can be used without additional functionalization and sample pre-treatment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366224 | PMC |
| http://dx.doi.org/10.1098/rsos.181557 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spontaneous Catalytic Reaction of a Surfactant in the Interfacial Microenvironment of Colloidal Gold Nanoparticles.
J Am Chem Soc
January 2025
State Key Laboratory of Marine Environmental Science, Fujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, Center for Marine Environmental Chemistry and Toxicology, College of the Environment and Ecology, Xiamen University, Xiamen 361102, China.
The performance of nanomaterials is significantly determined by the interfacial microenvironment, in which a surfactant plays an essential role as the adsorbent, but its involvement in the interfacial reaction is often overlooked. Here, it was discovered that citrate and ascorbic acid, the two primarily used surfactants for colloidal gold nanoparticles (Au NPs), can spontaneously undergo catalytic reaction with trace-level nitrogenous residue under ambient environment to form oxime, which is subsequently cleaved to generate CN or a compound containing the -CN group. Such a catalytic reaction shows wide universality in both reactants, including various carbonaceous and nitrogenous sources, and metal catalysts, including Au, Ag, Fe, Cu, Ni, Pt, and Pd NPs.
View Article and Find Full Text PDFUnlocking the Vitamin Puzzle: Investigating Levels in People With Alzheimer's Disease Versus Healthy Controls Through Systematic Review and Network Meta-Analysis.
J Hum Nutr Diet
February 2025
Department of Biostatistics and Medical Informatics, University College of Medical Sciences, Delhi, India.
The progression of Alzheimer's disease (AD) is intricately tied to the impairment of neurons, crucial for neurological functions. Despite extensive research, the precise mechanism underlying AD development remains elusive due to its multifaceted aetiology. Vitamin deficiency has emerged as a notable contributor to AD onset and progression, exerting a significant influence on brain function.
View Article and Find Full Text PDFUHPLC-MS/MS based comprehensive phenolic profiling, antimicrobial and antioxidant activities of Indian Rhodomyrtus tomentosa fruits.
Sci Rep
January 2025
Department of Biochemistry, CSIR-Central Food Technological Research Institute, Mysore, Karnataka, 570020, India.
Rhodomyrtus tomentosa fruits, endemic to the Western Ghats were analyzed for its free, bound and esterified phenolics by Ultra High Performance Liquid Chromatography-Mass Spectrometry. Overall, twenty-nine phenolic compounds were identified, amongst them 18 were detected in this fruit for the first time. Gallic acid (80.
View Article and Find Full Text PDFNavigating Bowel Preparation for Colonoscopy: A Comprehensive Overview.
J Clin Gastroenterol
December 2024
Department of Medicine.
Colorectal cancer (CRC) is the third most common cancer in the United States. Early detection through colonoscopy significantly improves survival rates. Detecting colon polyps depends on the quality of bowel preparation.
View Article and Find Full Text PDFImpact of cerium doping on the peroxidase-like activity of metal-organic frameworks.
Dalton Trans
January 2025
Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, Frontiers Science Center for Rare Isotopes, College of Chemistry and Chemical Engineering, Lanzhou University, 73000 Lanzhou, China.
Hydrogen peroxide, phenols, amines, aldehydes, and other substances can easily damage intracellular biomacromolecules. Although natural peroxidases can convert these harmful substances into benign ones, the high costs, poor stabilities, and stringent application conditions associated with these enzymes necessitate the exploration of artificial mimics. In this study, Ce-doped MIL-101(Fe)-NH and MIL-101(Fe)-NO were synthesized with varying compositions a solvothermal method.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!