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http://dx.doi.org/10.1302/2046-3758.81.BJR-2018-0235 | DOI Listing |
Genes Brain Behav
February 2025
Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), Paris, France.
Schizophrenia is a frequent and disabling disease. The persistence of the disorder despite its harmful consequences represents an evolutionary paradox. Based on recent discoveries in genetics, scientists have formulated the "price-to-pay" hypothesis: schizophrenia would be intimately related to human evolution, particularly to brain development and human-specific higher cognitive functions.
View Article and Find Full Text PDFEur Heart J
January 2025
Department of Epidemiology and Prevention, IRCCS NEUROMED, Via dell'Elettronica, 86077 Pozzilli, Italy.
Foods
November 2024
National Key Laboratory for Tropical Crop Breeding, School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), College of Tropical Agriculture and Forestry, Hainan University, Sanya 572025, China.
To characterize the nutrients and bioactive compounds in grape berries and to explore the real cause of the "French paradox" phenomenon, we performed metabolomic analysis of 66 grape varieties worldwide using liquid chromatography-tandem mass spectrometry (LC-MS). A nontargeted metabolomics approach detected a total of 4889 metabolite signals. From these, 964 bioactive and nutrient compounds were identified and quantified, including modified flavonoids, medicinal pentacyclic triterpenoids, vitamins, amino acids, lipids, etc.
View Article and Find Full Text PDFRev Infirm
December 2024
15 rue d'Auteuil, 44700 Orvault, France. Electronic address:
To hope is to bet on the future. Is this still possible at the end of life? The complex workings of the human psyche are such that, paradoxical as it may seem, hope and expectation sometimes remain right to the end of life. Continued hope is a resource.
View Article and Find Full Text PDFNihon Eiseigaku Zasshi
December 2024
Department of Preventive Medicine, Hyogo Medical University Faculty of Medicine.
The relationship between alcohol consumption and incident ischemic heart disease and stroke is characterized by a J- or U-shape. This denotes that light drinking has a preventive effect on cardiovascular diseases. Effects of alcohol drinking on lipid metabolism including an increase in HDL cholesterol concentration and a decrease in LDL cholesterol concentration are the main reasons for the anti-atherosclerotic action of alcohol.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!