We studied ethnomedical beliefs and utilization of alcohol herbal remedy for malaria in Uyo, south-coastal Nigeria. In-depth interviews were conducted with 213 respondents aged between 25 to 65 years, who were recruited through venue-based sampling. Malaria is recognized by its symptomatic presentations, which is reflected in different local names for the disease. Local etiological beliefs attribute malaria to mosquito bites, exposure to sunlight, fatigue, witchcraft, and excessive consumption of palm oil. There is a disease-specific preference for alcohol herbal remedies because they are accessible, affordable, and responsive to sociocultural realities. The therapy veils excessive consumption of alcohol with associated risks. Lack of quality control in production and dosage for the administration of these herbal remedies also put users at risk. Local beliefs should be integrated into malaria control programs to enhance community acceptance and participation. Herbal remedies should be subjected to regulation to ensure quality and minimize harms. Community health education should be mounted to improve knowledge of malarial transmission and promote utilization of appropriate health-care services.
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http://dx.doi.org/10.1177/0272684X18819978 | DOI Listing |
Phytother Res
January 2025
Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Brunei, Bandar Seri Begawan, Brunei.
The human body gets exposed to a variety of toxins intentionally or unintentionally on a regular basis from sources such as air, water, food, and soil. Certain toxins can be synthetic, while some are biological. The toxins affect the various parts of the body by activating numerous pro-inflammatory markers, like oxidative stresses, that tend to disturb the normal function of the organs ultimately.
View Article and Find Full Text PDFCurr Med Chem
January 2025
Department of Pharmaceutical Sciences, Shalom Institute of Health & Allied Sciences, Sam Higginbottom University of Agriculture, Technology & Sciences, Allahabad, 211007, Uttar Pradesh, India.
Background: Thymoquinone (TQ) is found in the seeds of Nigella sativa. It has immunomodulatory, antibacterial, anti-inflammatory, antioxidant, astringent, antifungal, and antihistaminic properties, making it a highly valuable compound of interest. However, the use of it as a therapeutic drug is highly challenging because of its poor solubility, low bioavailability, and short-term stability.
View Article and Find Full Text PDFComb Chem High Throughput Screen
January 2025
National Brain Research Centre, Manesar, Haryana, India 122052.
Introduction: The liver is essential for both the body's removal of waste materials and the metabolism of nutrients, it is critical for sustaining general health. However, a number of factors, including viral infections, immune system malfunctions, cancer, alcohol intake, and drug toxicity, are contributing to the rising prevalence of liver problems. Alternative approaches to liver disease treatment are being investigated due to the potential limitations of conventional medical treatments.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Jiangsu Key Laboratory of Regional Specific Resource Pharmaceutical Transformation, Huaiyin Institute of Technology, Huai'an 223003, China; National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization, Huaiyin Institute of Technology, Huai'an 223003, China. Electronic address:
Objective: To investigate the physicochemical properties, structural characteristics and in vitro activities of Shancigu polysaccharides to identify the authenticity of Shancigu, safeguard its medicinal value, and ensure the safety of its market distribution.
Methods: Eleven polysaccharides from different sources of Shancigu were obtained using water extraction and alcohol precipitation. Physicochemical properties were determined using colorimetry.
Vet World
November 2024
Division of Pathology, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia.
Background And Aim: , a nematode that frequently infects the digestive tract of chickens, is a significant concern for poultry health. In response, the use of medicinal plant-derived anthelmintics was proposed as a potential solution. This study observed the effectiveness of a single, graded dose of the ethanol extract of , L.
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