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Simultaneous prostatic and right seminal vesicle abscesses: a case report.
J Med Case Rep
November 2024
Department of Urology, La Rabta Hospital, University of Tunis El Manar, Tunis, Tunisia.
Background: Synchronous abscesses of the prostate and seminal vesicles represent a rare but clinically significant form of purulent retention. They pose diagnostic and therapeutic challenges and are associated with considerable morbidity and a high risk of sepsis.
Case Presentation: We present the case of a 60-year-old Caucasian man with a history of insulin-dependent diabetes mellitus, who had a voluminous prostatic abscess associated with a right seminal vesicle abscess due to compression of the right ejaculatory duct, and who presented to our department with sepsis.
Paired coral Sr/Ca and δO records reveal increasing ENSO influence on Malaysian Borneo's hydroclimate.
Sci Total Environ
December 2024
University of Leicester, 1 University Road, LE1 7RH Leicester, United Kingdom; Curtin Malaysia Research Institute, Curtin University Malaysia, Miri 98009, Malaysia; Molecular and Life Sciences, Curtin University, Bentley, WA 6102, Australia.
The El Niño Southern Oscillation (ENSO) is a worldwide climate phenomenon impacting temperatures and precipitation regimes across the globe. Previous studies have shown this climate phenomenon to influence Malaysian Borneo's hydroclimate. In the context of a changing climate and increasingly strong extreme ENSO events, understanding the influence of ENSO on this region, and its evolution through time, is essential to better constrain the future impacts it will have on the Maritime Continent's hydroclimate.
View Article and Find Full Text PDFA clinical case of pityriasis lichenoides chronica presenting with palpable purpura after streptococcal infection.
Folia Med (Plovdiv)
June 2024
Sofiamed University Hospital, St Kliment Ohridski University, Sofia, Bulgaria.
Article Synopsis
- Pityriasis lichenoides is a rare inflammatory skin condition characterized by red-brown papules and crusty lesions as they evolve over time.
- A 60-year-old woman developed the chronic form of this condition ten days after suffering from streptococcal pharyngitis, starting with purple spots on her legs and later developing red, scaly patches on other parts of her body.
- After treatment with methylprednisolone and hydroxychloroquine, her skin lesions improved significantly and did not return.
The 60-year evolution of lipid nanoparticles for nucleic acid delivery.
Nat Rev Drug Discov
September 2024
Department of Physiology & Biophysics, University of California, Irvine, CA, USA.
Delivery of genetic information to the interior of target cells in vivo has been a major challenge facing gene therapies. This barrier is now being overcome, owing in part to dramatic advances made by lipid-based systems that have led to lipid nanoparticles (LNPs) that enable delivery of nucleic acid-based vaccines and therapeutics. Examples include the clinically approved COVID-19 LNP mRNA vaccines and Onpattro (patisiran), an LNP small interfering RNA therapeutic to treat transthyretin-induced amyloidosis (hATTR).
View Article and Find Full Text PDFParaneoplastic leukocytosis secondary to carcinosarcoma: a report of two cases and literature review.
Chin Clin Oncol
June 2024
Medical Oncology Department, University Hospital of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Faculty of Medicine, University of Salamanca, Salamanca, Spain.
Background: Neutrophilia is an increase in the number of neutrophils over 7.5×103/µL. An increase in leukocytes over 50×103/µL is called a leukemoid reaction; and when it is associated with a solid tumor, it is considered a paraneoplastic syndrome called paraneoplastic leukemoid reaction (PLR).
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