In two recent studies in Molecular Cell, Wright et al. (2019) report complete spacer integration by a Cas1 mini-integrase and Edraki et al. (2019) describe accurate genome editing by a small Cas9 ortholog with less stringent PAM requirements.
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http://dx.doi.org/10.1016/j.molcel.2019.02.005 | DOI Listing |
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