The use of extracorporeal membrane oxygenation (ECMO) in severe hypothermia associated with cardiac arrest has become a more frequent warming technique in specialized centers over the years with better survival outcomes compared to traditional rewarming methods. We show that a full recovery is possible, even after prolonged resuscitation. We report the case of a 36-year old male who survived approximately 4 hours of cardiopulmonary resuscitation following an unknown duration of asystole in the context of severe accidental hypothermia (24°C). Normal sinus rhythm was obtained using a single external electric shock during the rewarming of the patient by ECMO. After a hospital stay of 17 days, there were no neurological deficits and he achieved a full recovery. Although prolonged out-of-hospital cardiac arrest has low survival rates and asystole is not generally considered as an indication for extracorporeal cardiopulmonary resuscitation (ECCPR), associated hypothermia can be a predictor of a possible positive outcome when ECMO is used as it reduces the metabolism and protects the brain, thus leading to "miraculous" recoveries with no neurological sequelae. This case demonstrates yet again the importance of advanced rewarming techniques such as ECMO in the outcome of patients with severe accidental hypothermia, even after prolonged and refractory out-of hospital cardiac arrest and when "no-flow" time is uncertain. It also highlights the need for accidental hypothermia treatment algorithms, especially in hospitals capable of ECMO rewarming, to enable more rapid decision-making.
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PLoS One
January 2025
Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
We aimed to determine whether emergency department (ED) overcrowding affects the occurrence of in-hospital cardiac arrest (IHCA) requiring resuscitation in the ED. This retrospective study was conducted in the ED of a single hospital. We applied the propensity score-matching method to adjust for differences in clinical characteristics in patients who visited the ED during overcrowded conditions.
View Article and Find Full Text PDFEur J Heart Fail
January 2025
Department for Internal Medicine and Cardiology, Technische Universität Dresden, Heart Centre Dresden, University Hospital, Dresden, Germany.
Aims: This study aimed to investigate incidence and predictors of weaning failure and in-hospital death after successful weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with cardiogenic shock (CS).
Methods And Results: Overall, 685 patients with CS treated with VA-ECMO from 23 tertiary care centres in 7 countries were analysed (median age 57 [interquartile range 49-66] years, 542 [79.1%] male, median lactate 7.
Kidney360
January 2025
Center for Cardiac Arrest Prevention, Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA, United States.
Background: Individuals with end-stage renal disease may be at increased risk of sudden cardiac arrest (SCA) associated with dialysis therapy. However, community-based studies with comprehensive adjudication of SCA are lacking.
Methods: We conducted a community-based study using a case-case study design in a US population of ≈1 million.
Brain Commun
December 2024
Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, 1011 Lausanne, Switzerland.
A key question for the scientific study of consciousness is whether it is possible to identify specific features in brain activity that are uniquely linked to conscious experience. This question has important implications for the development of markers to detect covert consciousness in unresponsive patients. In this regard, many studies have focused on investigating the neural response to complex auditory regularities.
View Article and Find Full Text PDFJACC Case Rep
January 2025
Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Structural abnormalities within the right ventricular outflow tract (RVOT) can present similarly to Brugada syndrome. A 34-year-old woman with no medical history presented with polymorphic ventricular tachycardia/ventricular fibrillation cardiac arrest and initial electrocardiogram showed type I Brugada pattern. Cardiac magnetic resonance imaging revealed prominent tissue thickening at the RVOT with late gadolinium enhancement.
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