Although the potential of plants extracts to improve feed efficiency and animal productivity and decrease methane emissions by enteric fermentation has been shown, the information available is often contradictory which has been attributed to differences in the complex mixture of bioactive compounds and their interactions. Understanding the degree to which structural features in a compound may affect the biological activity of an extract is essential. We hypothesised that relative small variations in the structure of a compound can have a significant influence on the ability of the derivatives to alter fermentation in the rumen. Nine compounds were synthetized from the natural alkaloid haemanthamine and tested in vitro for their effects on rumen protozoa and fermentation parameters. Our results showed that simple esterifications of haemanthamine or its derivative dihydrohaemanthamine with acetate, butyrate, pivalate or hexanoate led to compounds that differed in their effects on rumen fermentation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385227 | PMC |
| http://dx.doi.org/10.1038/s41598-019-38977-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In vitro gas production and rumen fermentation for diets containing increasing levels of Panicum maximum cv. Mombasa with or without spirulina.
Trop Anim Health Prod
January 2025
Animal Production Department, Faculty of Agriculture, Ain-Shams University, 68 Hadayek Shoubra, Cairo, 111241, Egypt.
This study was designed to evaluate the effect of substituting alfalfa hay with graded levels panicum maximum without or with graded levels of spirulina supplementation on rumen fermentation and nutrient degradability. The evaluation was achieved through an in vitro study, rumen fluid was obtained from adult sheep aged 2 years (fed clover hay), immediately after slaughter. Experimental diets were formulated as isonitrogenous and isocaloric and contained 40% forage.
View Article and Find Full Text PDFRumen-Degradable Starch Improves Rumen Fermentation, Function, and Growth Performance by Altering Bacteria and Its Metabolome in Sheep Fed Alfalfa Hay or Silage.
Animals (Basel)
December 2024
College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Alfalfa silage due to its high protein can lead to easier feeding management, but its high proportion of rumen-degradable protein can reduce rumen nitrogen utilization. Nevertheless, increasing dietary energy can enhance ruminal microbial protein synthesis. Thirty-two Suffolk female sheep were used in this study, with a 2 × 2 factorial arrangement of treatment.
View Article and Find Full Text PDFEffects of Dietary Protein Levels on Digestion, Metabolism, Serum Biochemical Indexes, and Rumen Microflora of Lanzhou Fat-Tailed Sheep.
Animals (Basel)
December 2024
School of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
This study aimed to investigate the effect of varying levels of dietary protein on digestion, metabolism, serum biochemical indexes, and rumen microflora in Lanzhou fat-tailed sheep. A total of twenty 8-month-old healthy rams with an initial average body weight (BW 25.16 ± 1.
View Article and Find Full Text PDFThe Effects of Mixed Inoculum Storage Time on In Vitro Rumen Fermentation Characteristics, Microbial Diversity, and Community Composition.
Animals (Basel)
December 2024
Jiangxi Province Key Laboratory of Animal Nutrition and Feed, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.
This study aimed to investigate the effects of different storage times of the mixed inoculum on in vitro rumen fermentation characteristics, microbial diversity, and community composition. The experiment was divided into five groups, with mixed inoculum composed of fresh rumen fluid and culture medium being stored at 39 °C for 0 h (H0), 12 h (H12), 24 h (H24), 36 h (H36), and 48 h (H48). After 48 h of in vitro fermentation, the fermentation fluid was collected to assess rumen fermentation characteristics and microbial community composition.
View Article and Find Full Text PDFThe effect of the biohydrogenation-induced milk fat depression in dairy cows on milk odd and branched chain fatty acids across multiple studies.
J Dairy Sci
January 2025
Department of Animal Science, Penn State University, University Park, 16802. Electronic address:
Diet-induced milk fat depression (MFD) caused by UFA, and low fiber diets results in an increase in alternate rumen biohydrogenation intermediates. The impact of these MFD-inducing diets on milk odd and branched chain fatty acids (OBCFA) is not well known. The first objective of this study was to characterize the time course of changes in OBCFA in milk fat during induction and recovery of MFD induced with a high UFA and low fiber diet in 3 separate experiments.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!