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http://dx.doi.org/10.3324/haematol.2018.209437 | DOI Listing |
J Dairy Sci
December 2024
Department of Agronomy, Food, Natural resources, Animals and Environment (DAFNAE), University of Padova, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
MicroRNAs (miRNAs) are short RNA molecules, typically 21-25 nucleotides long, synthesized within eukaryotic cells. They play a crucial role in coordinating complex gene expression regulatory networks. The miRNAs are involved in post-transcriptional regulation, either by degrading target mRNA or suppressing their transcription, thereby influencing protein translation.
View Article and Find Full Text PDFToxics
November 2024
Department of Toxicology, School of Public Health, Lanzhou University, Lanzhou 730000, China.
N-methyl-n'-nitroso-n'-nitroso guanidine (MNNG) can induce esophageal squamous cell carcinoma (ESCC), and microRNAs are associated with the development of ESCC and may serve as potential tumor prognostic markers. Thus, the aim of this study was to evaluate the potential function of miR-101-3p in MNNG-induced ESCC. An investigation of risk factors in patients with ESCC was carried out and the concentration of nine nitrosamines in urine samples was detected by the SPE-GC-MS technique.
View Article and Find Full Text PDFPeerJ
November 2024
Department of Ophthalmology, Changzheng Hospital of Naval Medical University, Shanghai, China.
Biomed Res Int
October 2024
Department of Nutrition, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Curcumin is a polyphenol compound with anticancer effects. We aimed to review the anti-neoplastic effects of curcumin on urogenital cancers, by regulating different microRNA expressions. A systematic search was conducted in Medline (PubMed), Embase, Scopus, and Web of Science up to the end of August 2024.
View Article and Find Full Text PDFJ Physiol Pharmacol
June 2024
Department of Endocrinology and Metabolism, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan City, Hubei Province, 442008, China.
Disorders of glucose and lipid metabolism are important causes of type 2 diabetes mellitus (T2DM). Defining the molecular mechanisms of metabolic disorders and exploring drug targets are key to the treatment of T2DM. The study discovered the effects of catalpol on insulin resistance (IR) and lipid metabolism disorder (LMD) in type 2 diabetes mellitus (T2DM).
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