AI Article Synopsis
- Septins are proteins first found in yeast that play important roles in various biological functions across species, including humans.
- Recent research highlights the role of Septins in neurodevelopment, particularly in how they help neurons develop and compartmentalize properly.
- The review discusses new findings on how Septins affect neuron differentiation, comparing their functions in neurons and yeast.
Article Abstract
Septins, discovered almost half a century ago in yeast, have prominent contributions in a broad range of morphological and functional processes from yeast to human. Septins now emerge as key players of neurodevelopment and more specifically of the mechanisms driving the complex morphological differentiation and compartmentalization of neurons that are fundamental to their function. We review here recent advances in Septin-mediated processes of neuron differentiation, which enlighten similarities and differences between neuron and yeast polarity programs.
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| http://dx.doi.org/10.1016/j.conb.2019.01.012 | DOI Listing |
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