AI Article Synopsis
- Tritrichomonas foetus is the cause of Bovine Trichomonosis (BT), a significant health issue in Argentina that leads to reproductive problems and economic losses for cattle farmers.
- Metronidazole, the main treatment for BT, only offers temporary relief and is becoming less effective due to increasing drug resistance both in laboratory and real-world settings.
- This study examines the susceptibility of six T. foetus isolates under different oxygen conditions, revealing higher resistance levels than previously documented, and aims to inform better treatment strategies in Argentina.
Article Abstract
Background: Tritrichomonas foetus is the etiologic agent of the sexually transmitted disease Bovine Trichomonosis (BT). In Argentina, BT is endemic and represents a relevant health problem that causes reproductive inefficiency in cattle and large economic losses. Metronidazole is the drug of choice in the treatment of BT. Treatment has been associated with a temporary resolution of the clinical signs but is not able to control the disease. In recent years, the apparition of in vivo and in vitro aerobic and anaerobic resistance leading to ineffective treatments has been reported.
Aims: Thus, the aim of the present study was to explore the susceptibility of six different isolates of T. foetus under aerobic (AC) and anaerobic (ANC) conditions.
Results And Discussion: Six isolates of T. foetus were obtained from samples of preputial smegma of bovine origin. Values of minimum lethal concentration and minimum inhibitory concentration were higher than those observed in other works and represent current data in Argentina and provide information to establish new treatment protocols.
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| http://dx.doi.org/10.2478/s11686-019-00031-1 | DOI Listing |
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