AI Article Synopsis
- - The study assessed how effective ceftazidime-avibactam is alone and in combination with meropenem against 11 multi-drug resistant bacteria, particularly those with oxacillinases.
- - Results showed that ceftazidime-avibactam worked really well, especially when used with meropenem, against these resistant strains.
- - The disk approximation method used in the study effectively identified synergistic interactions in the treatment of infections.
Article Abstract
Susceptibility of ceftazidime-avibactam and synergy with meropenem were investigated using disk approximation and time-kill assays against 11 multiresistant isolates harboring oxacillinases and 5 isolates carrying Ceftazidime-avibactam was very active and synergistic with meropenem against multiresistant isolates. On the other hand, only the isolates coharboring and displayed synergy. The disk approximation technique presented good sensitivity for synergism in infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496051 | PMC |
| http://dx.doi.org/10.1128/AAC.02367-18 | DOI Listing |
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