Many pathogens must bind to entry receptors on the surfaces of host cells yet avoid any closely-related phagocytic decoy receptors on granulocytes that evolved as a host defense mechanism. The discovery of decoy-receptor polymorphisms in human populations now points to an evolutionary process that allows the host to catch up with pathogens.
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http://dx.doi.org/10.1016/j.cub.2018.12.006 | DOI Listing |
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