Histoplasmosis is a mycosis caused by the dimorphic fungus, , which is transmitted via dust and aerosols. Lung involvement is the most common, with a varied clinical presentation. Although it is not the only source of infection, is frequently found in bat guano, which is the reason why it is highly prevalent among caving practitioners. The solitary histoplasmoma of the lung is an unusual and chronic manifestation of this entity, which mimics, or at least is frequently misconstrued, as a malignancy. Almost invariably, the diagnosis of this type of histoplasmosis presentation is achieved after lung biopsy. The authors present the case of a young woman who sought medical care because of chest pain. The diagnostic work-up revealed the presence of a pulmonary nodule. She was submitted to a thoracotomy and wedge pulmonary resection. The histologic analysis rendered the diagnosis of histoplasmoma. This report aims to call attention to this diagnosis as the differential diagnosis of a pulmonary nodule.
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http://dx.doi.org/10.4322/acr.2018.065 | DOI Listing |
Front Oncol
December 2024
Honorary Research Associate, Department of Operations and Quality Management, Durban University of Technology, Durban, South Africa.
Introduction: Lung cancer is one of the main causes of the rising death rate among the expanding population. For patients with lung cancer to have a higher chance of survival and fewer deaths, early categorization is essential. The goal of thisresearch is to enhance machine learning to increase the precision and quality of lung cancer classification.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Department of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Background: The intricate anatomical variations in lung structure often perplex thoracic surgeons, and the accurate identification of these variations is closely associated with favorable surgical outcomes.
Case Presentation: A 53-year-old female patient who underwent computed tomography (CT) examination due to chest discomfort, revealing the presence of a partial solid nodule highly suspected of early-stage lung cancer, measuring approximately 2.8 × 2.
BMC Med Imaging
January 2025
Department of Radiology, The First Affiliated Hospital of Yangtze University, No. 40 Jinlong Road, Shashi District, Jingzhou, Hubei, 434000, China.
Objective: The study aimed to evaluate the application value of computed tomography (CT) three-dimensional (3D) reconstruction technology in identifying benign and malignant lung nodules and characterizing the distribution of the nodules.
Methods: CT 3D reconstruction was performed for lung nodules. Pathological results were used as the gold standard to compare the detection rates of various lung nodule signs between conventional chest CT scanning and CT 3D reconstruction techniques.
Crit Rev Oncol Hematol
January 2025
Department of Respiratory and Critical Care Medicine, Institute of Respiratory Health, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Institute of Respiratory Health, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Precision Medicine Center, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:
Lung cancer is the leading cause of cancer-related mortality worldwide, highlighting the urgent need for more accurate and minimally invasive diagnostic tools to improve early detection and patient outcomes. While low-dose computed tomography (LDCT) is effective for screening in high-risk individuals, its high false-positive rate necessitates more precise diagnostic strategies. Liquid biopsy, particularly ctDNA methylation analysis, represents a promising alternative for non-invasive classification of indeterminate pulmonary nodules (IPNs).
View Article and Find Full Text PDFChest
January 2025
Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing, China. Electronic address:
Background: Patients with pulmonary subsolid nodules (SSNs) ≤ 2 cm in diameter and a consolidation-to-tumor ratio (CTR) ≤ 0.25 have good postoperative prognoses, but their management remains controversial.
Research Question: Does upfront surgical intervention lead to higher survival than watchful waiting in patients with SSNs diameter ≤ 2 cm and CTR ≤ 0.
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