Crossed cerebellar diaschisis (CCD) represents the reduction of blood flow, metabolism, and oxygen consumption in the cerebellar hemisphere contralateral to a cerebral focal lesion. This phenomenon is the result of remote metabolic effects of cerebral lesions and it has been described since the first attempts for functional imaging of the brain, almost 40 years ago. Nevertheless, its clinical significance remains uncertain and new ways to use imaging of CCD for prognosis or assessment of novel therapies are being investigated. In this report, we present treatment for glioblastoma as a cause of CCD imaged on positron emission tomography/computed tomography with (F) fluoro-D-glucose in our department.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357717PMC
http://dx.doi.org/10.4103/wjnm.WJNM_15_18DOI Listing

Publication Analysis

Top Keywords

crossed cerebellar
8
cerebellar diaschisis
8
positron emission
8
emission tomography/computed
8
tomography/computed tomography
8
tomography fluoro-d-glucose
8
treatment glioblastoma
8
case crossed
4
diaschisis follow-up
4
follow-up positron
4

Similar Publications

Background: Data regarding long-term recovery from autoimmune encephalitis (AE) remain limited.

Methods: This retrospective observational study investigated outcomes in 182 patients who met the 2016 criteria for definite AE. Recovery data were available in 172 patients.

View Article and Find Full Text PDF

Introduction: White matter (WM) tract degeneration is a characteristic feature of progressive supranuclear palsy (PSP), with longitudinal changes observed in PSP-Richardson's syndrome (PSP-RS). Little, however, is known about the other PSP variants. We assessed cross-sectional and longitudinal WM degeneration across PSP variants using diffusion tractography.

View Article and Find Full Text PDF

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant (AD) neurodegenerative disorder prevalent in the Americas, particularly in Mexico. Clinical manifestations include progressive ataxia and epilepsy. However, it can exhibit wide phenotypic variability and even reduced penetrance.

View Article and Find Full Text PDF

Sleep and breathing in children with Joubert syndrome and a review of other rare congenital hindbrain malformations.

Ther Adv Respir Dis

January 2025

Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, 4800 Sand Point Way NE, OC 7.730, Seattle, WA 98105, USA.

Background: Joubert syndrome (JS) is an autosomal recessive disorder with a distinctive mid-hindbrain malformation known as the "molar tooth sign" which involves the breathing control center and its connections with other structures. Literature has reported significant respiratory abnormalities which included hyperpnea interspersed with apneic episodes during wakefulness. Larger-scale studies looking at polysomnographic findings or subjective reports of sleep problems in this population have not yet been published.

View Article and Find Full Text PDF

Neurobiological fingerprints of negative symptoms in schizophrenia identified by connectome-based modeling.

Psychiatry Clin Neurosci

January 2025

Department of Radiology, and Functional and Molecular Imaging key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China.

Aim: As a central component of schizophrenia psychopathology, negative symptoms result in detrimental effects on long-term functional prognosis. However, the neurobiological mechanism underlying negative symptoms remains poorly understood, which limits the development of novel treatment interventions. This study aimed to identify the specific neural fingerprints of negative symptoms in schizophrenia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!