Large number of microflora is parasitized in the human intestinal tract, which maintains the stability of the microecological environment in the host's intestinal tract and the healthy state of the body. Once the steady state is out of balance, the intestinal microflora is dysfunctional and a variety of diseases will be induced. Acupuncture and moxibustion have a positive role in improving different types of clinical problems by regulating , harmonizing and , and strengthening the body's resistance. At present, researches on the effect of acupuncture and moxibustion interventions on intestinal microflora mainly focuses on the following aspects 1) adjusting the count and proportion of the intestinal microflora to recover its stability, 2) improving gastrointestinal motility disorder by promoting the interaction between intestinal microflora and brain-gut axis (brain-gut peptides), and ameliorating the intestinal barrier function by reducing levels of proinflammatory cytokines to suppress inflammatory reactions. In the future, the research should pay more attention to the holistic regulatory function of acupuncture and moxibustion, the acupoint specificity, acupoint combination and different intervention measures, as well as the optimization of clinical regimen, so as to better intestinal microflora regulation.
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http://dx.doi.org/10.13702/j.1000-0607.180118 | DOI Listing |
Curr Microbiol
January 2025
Dairy Department, National Research Centre, Dokki, Cairo, Egypt.
The beneficial impact of gut microbiota on human health has encouraged studies on factors modulating it. Among the different factors, diet plays a vital role in this area. Many studies on animals and humans have been concerned with the effects of fermented milk products on gut microbiota and how they relate to health benefits.
View Article and Find Full Text PDFVopr Pitan
January 2025
Ufa University of Science and Technology, 450076, Ufa, Russian Federation.
The most common mechanism of the development of cardiovascular diseases is atherosclerosis, caused by genetic predisposition, hyperlipidemia, inflammation and metabolic disorders. Statins used in medicine inhibit endogenous cholesterol synthesis, but are characterized by diabetogenic effect, development of intolerance in 9.1%, and muscle symptoms in 10-25% of patients.
View Article and Find Full Text PDFMed Sci (Paris)
January 2025
Département de microbiologie fondamentale, université de Lausanne, Lausanne, Suisse.
The gut microbiome plays an important role in animal physiology and development. While the molecular, cellular and ecological mechanisms that determine its diversity and impact on animal health are beginning to unfold, we still know relatively little about its evolutionary history. Fundamental questions such as "Is the microbiota evolving and at what race?", "What are its origins?", "What are the consequences of microbiota evolution for human health?" or "Did we co-evolve with our gut bacteria?" are only beginning to be explored.
View Article and Find Full Text PDFJ Med Microbiol
January 2025
Department of Medical Sciences, Faculty of Medicine & Health Sciences, Universiti Sains Islam Malaysia (USIM), Nilai, Negeri Sembilan, Malaysia.
Type 2 diabetes mellitus (T2DM) is a major global health issue projected to exceed 700 million cases by 2045. In Malaysia, T2DM prevalence has risen, with notable ethnic disparities. The gut microbiota's role in T2DM pathogenesis is well recognized, yet its composition in Malaysia's ethnically diverse population remains underexplored.
View Article and Find Full Text PDFJ Med Microbiol
January 2025
Shenzhen Bao'an Authentic TCM Therapy Hospital, Shenzhen 518000, PR China.
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that presents significant challenges in terms of treatment owing to a pronounced likelihood of recurrence and an elevated risk of cancer development, thereby imposing substantial risks on affected individuals. The gut microbiota of Firmicutes and Bacteroidetes (F/B) can affect diseases associated with IBD, which is also a risk factor for breast cancer. This review discusses the hazards associated with UC, highlights the existing disparities in UC-associated gut microbiome research, explores the concept of the F/B ratio and scrutinizes its correlation with UC.
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