Babies born to mothers with gestational diabetes mellitus (GDM) are at a greater risk of developing respiratory complications and hypoglycaemia than those born to mothers without diabetes. However, there is currently insufficient evidence as to whether these risks are altered by antenatal corticosteroids after 37 weeks gestation. This retrospective study suggests that antenatal corticosteroids probably reduce respiratory admissions to the newborn intensive care unit with a mild increase in neonatal hypoglycaemia in women with GDM who deliver via caesarean section after 37 weeks gestation. Consequently, we recommend a randomised, controlled trial is required to determine the efficacy and safety of antenatal corticosteroids specifically in women with GDM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/ajo.12963 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Personalized Antenatal Corticosteroid Therapy and Central Nervous System Development: Reflections on the Gold Standard of Fetomaternal Therapy.
Diseases
December 2024
Department of Obstetrics and Gynecology and CERICSAL (Centro di Ricerca Clinico SALentino), "Veris delli Ponti Hospital", Via Giuseppina Delli Ponti, 73020 Scorrano, Lecce, Italy.
Background: The term "fetal programming" refers to the effects of endogenous and exogenous corticosteroids, whether received from the mother or the fetus, on brain development and the hypothalamic-pituitary-adrenal axis reset. The authors of this narrative review examine the WHO's guidelines for prenatal corticosteroids in pregnant women who are at high risk of premature delivery. These guidelines are regarded as the best available for preventing late-life problems resulting from preterm.
View Article and Find Full Text PDFDelivery mode and risk of intraventricular hemorrhage: A retrospective single-center study on 1760 preterm infants of less than 32 weeks.
Eur J Obstet Gynecol Reprod Biol
December 2024
Department of Odontostomatologic and Specialized Clinical Sciences, Polytechnic University of Marche, Ancona, Italy; Division of Neonatology, Mother and Child Department, G. Salesi Children's Hospital, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy.
Objective: To evaluate the association between delivery mode and intraventricular hemorrhage (IVH) in infants with a gestational age (GA) < 32 weeks.
Study Design: We retrospectively reviewed data of 1760 infants with a GA between 24 and 31 weeks/days born between 01.01.
OPtimal TIming of antenatal COrticosteroid administration in pregnancies complicated by early-onset fetal growth REstriction: results of a large, multicenter cohort study (the OPTICORE study).
Am J Obstet Gynecol
December 2024
department of Obstetrics and Gynaecology, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, and department of Obstetrics and Gynaecology, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address:
Background: Early-onset fetal growth restriction as consequence of placental insufficiency frequently requires iatrogenic, preterm birth. Administration of antenatal corticosteroids reduces risks of neonatal morbidity and mortality following preterm birth and is most beneficial if the neonate is delivered within two weeks following treatment. International guidelines on fetal growth restriction pregnancies do not provide directives regarding the timing of antenatal corticosteroids, resulting in practice variation.
View Article and Find Full Text PDFMaternal and neonatal outcomes following antenatal corticosteroids in pregnancies complicated by diabetes: a scoping review.
AJOG Glob Rep
November 2024
Department of Obstetrics, Gynaecology & Newborn Health, The University of Melbourne, Parkville, Victoria, Australia (Atallah, Moon and Said).
Article Synopsis
- The text reviews current research on the use of antenatal corticosteroids in pregnancies complicated by diabetes, focusing on maternal and neonatal outcomes.
- A systematic search identified 19 studies, but results varied widely due to differences in clinical settings and types of corticosteroids used.
- The review concluded that there is no strong evidence supporting the benefit of corticosteroids for improving neonatal respiratory outcomes in these pregnancies, with mixed results on neonatal hypoglycemia.
Risk factors and nomogram for the prediction of intracranial hemorrhage in very preterm infants.
BMC Pediatr
December 2024
Department of Neonatology, Dongguan Maternal and Child Health Care Hospital, Dongguan, 523000, China.
Aims: This study aims to identify important risk factors for intracranial hemorrhage (ICH) in very preterm infants at our institution and develop a predictive nomogram for early detection of ICH.
Methods: We retrospectively analyzed neonates with a gestational age (GA) under 32 weeks, admitted to the neonatal intensive care unit from March 2022 to July 2023. Infants were categorized into two groups based on ultrasound findings and assessed for thirteen variables including gender, GA, birth weight (BW), acidosis, among others.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!