[Orosomucoid and sialic acid - structure, functions, clinical relations].

The work focuses on orosomucoid. First, the biological role and the development of this essential molecule is summarized, then the formation of its special molecular structure is introduced. After the summary of the specific characteristics and the physiological, pathophysiological as well as clinical properties of orosomucoid and sialic acid, their most important roles are also presented. Orosomucoid belongs to the family of lipocalins and the subfamily of immunocalins - this determines its immunological, anti-inflammatorical and transporting capacities. Another important quality of the molecule is that it is recognized by lectins. Orosomucoid is highly bioactive. More knowledge is increasing about its function and biological role. The clinical relations are summarised, too. Orv Hetil. 2019; 160(8): 283-290.