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Case report: Intra-abdominal inflammatory myofibroblastic tumor with mucinous features: a case of rapid recurrence and dissemination post-surgery.
Front Oncol
January 2025
Department of Radiology, People's Hospital of Deyang City, Deyang, Sichuan, China.
Inflammatory myofibroblastic tumors (IMTs) are rare mesenchymal neoplasms with intermediate biological potential and are characterized by spindle-shaped myofibroblastic cells and significant inflammatory infiltrates. This case report describes a 24-year-old male with diabetes who was admitted to the hospital for over three days of vomiting and abdominal pain and was initially diagnosed with diabetic ketoacidosis. Upon admission, an abdominal CT scan revealed a large cystic-solid mass in the abdominal cavity and multiple nodules in the mesentery, omentum, and peritoneum, suggesting a preliminary diagnosis of an intra-abdominal mesenchymal tumor with peritoneal metastasis.
View Article and Find Full Text PDFPerC B-Cells Activation via Thermogenetics-Based CXCL12 Generator for Intraperitoneal Immunity Against Metastatic Disseminated Tumor Cells.
Adv Mater
January 2025
Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Environmental Science and Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, 410082, China.
During cancer peritoneal metastasis (PM), conventional antigen-presenting cells (dendritic cells, macrophages) promote tumorigenesis and immunosuppression in peritoneal cavity. While intraperitoneal immunotherapy (IPIT) has been used in clinical investigations to relieve PM, the limited knowledge of peritoneal immunocytes has hindered the development of therapeutic IPIT. Here, a dendritic cell-independent, next-generation IPIT is described that activates peritoneal cavity B (PerC B) cell subsets for intraperitoneal anti-tumor immunity via exogenous antigen presentation.
View Article and Find Full Text PDFToxoplasmal meningoencephalitis in a 14 week-old shelter cat with presumed feline infectious peritonitis.
Vet Parasitol Reg Stud Reports
January 2025
Department of Microbiology & Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA; Department of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA; Feline Health Center, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA. Electronic address:
Toxoplasmal meningoencephalitis is a sporadic condition that is often misdiagnosed antemortem, frequently resulting in euthanasia especially in resource-limited settings. Here we report a case of a 7-week-old female domestic shorthair cat from an animal shelter who presented in a compromised condition and continued to display clinical signs consistent with a "failure to thrive" kitten. Weight loss and decreased activity were observed, and later on, neurological dysfunction became apparent.
View Article and Find Full Text PDFDisseminated Leiomyomatosis Following a Robotic-Assisted Myomectomy With Power Morcellation: A Case Report.
Cureus
December 2024
Obstetrics and Gynecology, Vassar Brothers Medical Center, Poughkeepsie, USA.
This case reports a 44-year-old female who presented to the gynecologic oncology clinic status post robotic-assisted laparoscopic myomectomy with intraperitoneal unprotected power morcellation in 2012, with an incidental finding of three conglomerate solid masses in the abdomen above the uterus, with each mass measuring approximately 15.5 cm. The patient underwent an exploratory laparotomy where multiple masses greater than 10 cm were found scattered throughout the abdominal cavity.
View Article and Find Full Text PDFPrognostic significance of right subdiaphragmatic washing cytology in patients with endometrial cancer.
Sci Rep
January 2025
Department of Gynecologic Oncology, National Hospital Organization (NHO) Shikoku Cancer Center, Ko-160 Minami-Umemoto, Matsuyama, 7910280, Japan.
Cancer cells in the right subdiaphragmatic lavage may reflect peritoneal dissemination, but its prognostic significance is unknown. This study investigated recurrence-free survival (RFS), overall survival (OS), and recurrence patterns in patients with curatively resected endometrial cancer by cytology collection site. Peritoneal cytology was collected at the beginning of surgery by washing the pelvic and right subdiaphragmatic cavity separately.
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