Cancer is becoming a major reason for death troll worldwide due to the difficulty in finding an efficient, cost effective and target specific method of treatment or diagnosis. The variety of cancer therapy used in the present scenario have painful side effects, low effectiveness and high cost, which are some major drawbacks of the available therapies. Apart from the conventional cancer therapy, nanotechnology has grown extremely towards treating cancer. Nanotechnology is a promising area of science focusing on developing target specific drug delivery system for carrying small or large active molecules to diagnose and treat cancer cells. In the field of nanoscience, Chitosan nanopolymers (ChNPs) are been emerging as a potential carrier due to their biodegradability and biocompatibility. The easy modification and versatility in administration route of ChNPs has attracted attention of researchers towards loading chemicals, proteins and gene drugs for target specific therapy of cancer cells. Therefore, the present review deals with the growing concern towards cancer therapy, introduction of ChNPs, mode of action and other strategies employed by researchers till date towards cancer treatment and diagnosis ChNPs.
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http://dx.doi.org/10.1016/j.ijbiomac.2019.02.060 | DOI Listing |
Implement Sci Commun
January 2025
Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, IL, Chicago, USA.
Background: Studies have demonstrated that standardizing labor induction (IOL), often with the use of protocols, may reduce racial inequities in obstetrics. IOL protocols are complex, multi-component interventions. To target identified implementation barriers, audit and feedback (A&F) was selected as an implementation strategy.
View Article and Find Full Text PDFEpigenetics Chromatin
January 2025
Department of Biomedical Sciences, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, Malaysia.
Despite significant advances in HIV treatment, a definitive cure remains elusive. The first-in-human clinical trial of Excision BioTherapeutics' CRISPR-based HIV cure, EBT-101, demonstrated safety but failed to prevent viral rebound. These outcomes may result from the interplay of several factors.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Health Behavior and Social Medicine, West China School of Public Health and West China Fourth Hospital, Research Center for Palliative Care, West China-PUMC C.C. Chen Institute of Health, Sichuan University, Chengdu, P.R. China.
Background: The promotion of healthy dietary behaviors in adolescence is critical, which have long-term implications for lifelong health. Integration is an important method for improving limited theories of dietary behavior change. The present study proposes an integrated model aimed at identifying the diverse determinants of healthy dietary behaviors in adolescents and assesses its stage-specific nature as the potential for effective interventions.
View Article and Find Full Text PDFJ Transl Med
January 2025
Department of Cardiology, Tongji Hospital, School of Medicine, Tongji University, No. 389 Xincun Road, Shanghai, 200065, China.
Background: Heavy metal exposure is an emerging environmental risk factor linked to cardiovascular disease (CVD) through its effects on vascular ageing. However, the relationship between heavy metal exposure and vascular age have not been fully elucidated.
Methods: This cross-sectional study analyzed data from 3,772 participants in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2016.
BMC Psychiatry
January 2025
Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran.
Introduction: Mental disorders, such as anxiety and depression, significantly impacted global populations in 2019 and 2020, with COVID-19 causing a surge in prevalence. They affect 13.4% of the people worldwide, and 21% of Iranians have experienced them.
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