Laparoscopic gastric greater curvature plication (LGGCP) has been presented as an alternative to laparoscopic sleeve gastrectomy (LSG) for reversible reduction of stomach capacity without gastric reduction or stapling. We present a case of a 51-year-old Hispanic female with a BMI of 41.91 kg/m, who underwent (LGGCP) 5 years previously at another institution. Despite multiple interventions, the patient was unable to successfully lose weight, and the decision was made to reverse the procedure with a robot-assisted Roux-en-Y gastric bypass. The plication was intact extending from the fundus to the antrum, with the sutures incorporated by scarring and fibrotic tissue. Sutures were delicately removed to form a 30-cc pouch, followed by jejuno-jejunal and gastrojejunal anastomosis. The patient tolerated the surgery well and control fluoroscopy was negative for anastomotic leaks, patient was discharged home on POD 2. At the 40-day follow-up, the patient had lost 22 lb., reducing her BMI to 37.64 kg/m. The 3D vision of the robotic camera and the six degrees of freedom of the robotic instruments seemed to facilitate the challenging dissection of the embedded sutures used for the LGGCP and its overall undoing. However, further volume and data on the robotic approach for this specific revisional procedure are necessary before drawing any definitive conclusions.
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http://dx.doi.org/10.1007/s11695-019-03721-x | DOI Listing |
Background: Transoral outlet reduction endoscopy (TORe) and glucagon-like peptide-1 agonist, liraglutide, have individually shown promise in managing weight regain after Roux-en-Y gastric bypass. However, combined effects of adjunctive liraglutide to TORe remain unexplored. A cross-over design was utilized to evaluate the efficacy of liraglutide treatment when initiated immediately post-TORe or 1 year post-TORe.
View Article and Find Full Text PDFArq Bras Cir Dig
January 2025
Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Department of Gastroenterology - São Paulo (SP), Brazil.
Eur J Nucl Med Mol Imaging
January 2025
Departments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Purpose: Trophoblast cell-surface antigen 2 (Trop2) is overexpressed in various solid tumors and contributes to tumor progression, while its expression remains low in normal tissues. Trop2-targeting antibody-drug conjugate (ADC), sacituzumab govitecan-hziy (Trodelvy), has shown efficacy in targeting this antigen. Leveraging the enhanced specificity of ADCs, we conducted the first immunoPET imaging study of Trop2 expression in gastric cancer (GC) and triple-negative breast cancer (TNBC) models using Zr-labeled Trodelvy ([Zr]Zr-DFO-Trodelvy).
View Article and Find Full Text PDFJDS Commun
January 2025
Department of Animal Science, University of Florida, Gainesville, FL 32611.
The objective of this study was to compare fermentation profile and microbial diversity from rumen samples collected using a rumen cannula (RC) or stomach tube (ST) in lactating dairy cows. Three ruminally cannulated lactating dairy cows were used in a 3 × 3 Latin square design. The experimental period was 28 d and rumen fluid was collected 4 h after feeding on d 22 and 26 of each experimental period.
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