Introduction: The aim of this work is to report diagnostic reference levels (DRLs) for hybrid positron emission tomography and x-ray computed tomography (PET/CT) exams in Australia (AU) for Queensland (QLD) and Western Australia (WA) (AU QLD/WA) and New Zealand (NZ).
Methods: Two-structured booklets were designed to collect dose information, patient demographics, equipment details and acquisition protocols for fluoride-18 fluorodeoxyglucose ( F-FDG) PET/CT procedures, and any additional diagnostic CT routinely performed as part of F-FDG whole-body examination. The DRL was reported based on the 75 percentile and achievable dose for F-FDG, CT dose index volume (CTDI ) and dose length product (DLP). The effective dose and total effective dose was reported for F-FDG whole-body PET/CT examination. Also, the effective dose was reported separately for identified additional diagnostic CT.
Results: The findings of this study show that the current DRL for F-FDG in AU QLD/WA and NZ was 333.75 MBq and 332.87 MBq, respectively. The reported AU QLD/WA CTDI and DLP associated with F-FDG whole-body PET/CT examinations from vertex to thigh (VT) was 4.41 mGy and 474 mGy.cm. In NZ, the reported VT CTDI and DLP was 13.07 mGy and 1319.05 mGy.cm. The effective dose for F-FDG and CT component was 5.6 mSv and 4.7 mSv for AU QLD/WA. For NZ, the effective dose was 5.7 mSv and 10.9 mSv for F-FDG and CT component. The total effective dose delivered from the F-FDG whole-body scan from the AU QLD/WA PET/CT centres (10.44 mSv) were lower than the radiation doses delivered from the NZ (16.65 mSv).
Conclusions: The current DRLs were proposed for AU QLD/WA and NZ for F-FDG whole-body PET/CT examinations. Variations existed in the current practice of AU QLD/WA and NZ PET/CT examinations. There is a need to optimize the radiation doses delivered from PET/CT examinations.
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http://dx.doi.org/10.1111/1754-9485.12857 | DOI Listing |
Cell Transplant
January 2025
Department of Hematology, 920th Hospital of Joint Logistics Support Force, Kunming, China.
Donor-specific antibodies (DSAs) are essential causes of graft rejection in haploidentical hematopoietic stem cell transplantation (haplo-HSCT). DSAs are unavoidable for some patients who have no alternative donor. Effective interventions to reduce DSAs are still needed, and the cost of the current therapies is relatively high.
View Article and Find Full Text PDFEnviron Toxicol Chem
January 2025
Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, Yolo County, CA, 95616USA.
Juvenile Chinook Salmon (Oncorhynchus tshawytscha) populations have decreased substantially in the Sacramento-San Joaquin Delta (Delta) over the past decades, so considerably that two of the four genetically distinct runs are now listed in the Endangered Species Act. One factor responsible for this decline is the presence of contaminants in the Delta. Insecticides, used globally in agricultural, industrial, and household settings, have the potential to contaminate nearby aquatic systems through spray drift, runoff, and direct wastewater discharge.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
January 2025
Department of Physics, Faculty of Sciences, Arak University, Arak, Iran.
Objective: Addressing the rising cancer rates through timely diagnosis and treatment is crucial. Additionally, cancer survivors need to understand the potential risk of developing secondary cancer (SC), which can be influenced by several factors including treatment modalities, lifestyle choices, and habits such as smoking and alcohol consumption. This study aims to establish a novel relationship using linear regression models between dose and the risk of SC, comparing different prediction methods for lung, colon, and breast cancer.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
January 2025
Department of Genetics, Zanjan Branch, Islamic Azad University, Zanjan, Iran.
Background: Acute Lymphoblastic Leukemia (ALL) is the most common type of leukemia among children. There are several types of drugs that are common in treating and controlling leukemia, including 6-M. Moreover, the anti-cancer effects of the Thiosemicarbazone-Ni complex were surveyed as well as 6-MP.
View Article and Find Full Text PDFNeurogastroenterol Motil
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Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Background: The carbon-13 spirulina gastric emptying breath test (GEBT) is approved to identify delayed, but not accelerated, gastric emptying (GE). We compared the utility of the GEBT to scintigraphy for diagnosing abnormal GE in patients with diabetes mellitus.
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