We report a multimicrojoule, ultrabroadband midinfrared optical parametric amplifier based on a GaSe nonlinear crystal pumped at ∼2 μm. The generated idler pulse has a flat spectrum spanning from 4.5 to 13.3 μm at -3 dB and 4.2 to 16 μm in the full spectral range, with a central wavelength of 8.8 μm. The proposed scheme supports a subcycle Fourier-transform-limited pulse width. A (2+1)-dimensional numerical simulation is employed to reproduce the obtained idler spectrum. To our best knowledge, this is the broadest -3 dB spectrum ever obtained by optical parametric amplifiers in this spectral region. The idler pulse energy is ∼3.4 μJ with a conversion efficiency of ∼2% from the ∼2 μm pump to the idler pulse.
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http://dx.doi.org/10.1364/OL.44.001003 | DOI Listing |
Sci Rep
January 2025
Department of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil, Iran.
In this paper, we propose and theoretically investigate a novel multimode refractive index (MMRI) plasmonic optical sensor for detecting various brain cancer cells, leveraging the unique capabilities of split ring resonators (SRRs). The sensor, simulated using the finite-difference time-domain (FDTD) method, exhibits dual resonance modes in its reflection spectrum within the 1500 nm to 3500 nm wavelength range, marking a significant advancement in multimode plasmonic biosensing. Through detailed parametric analysis, we optimize critical dimensional parameters to achieve superior performance.
View Article and Find Full Text PDFJ Biomed Opt
December 2024
University of Kentucky, Department of Biomedical Engineering, Lexington, Kentucky, United States.
Significance: Cellular metabolism is highly dynamic and strongly influenced by its local vascular microenvironment, gaining a systems-level view of cell metabolism is essential in understanding many critical biomedical problems in a broad range of disciplines. However, very few existing metabolic tools can quantify the major metabolic and vascular parameters together in biological tissues with easy access.
Aim: We aim to fill the technical gap by demonstrating a point-of-care, easy-to-use, easy-to-access, rapid, systematic optical spectroscopy platform for metabolic and vascular characterizations on biological models to enable scientific discoveries to translate more efficiently to clinical interventions.
Philos Trans A Math Phys Eng Sci
December 2024
Istituto di Fotonica e Nanotecnologie del CNR, Piazza Leonardo da Vinci 32, Milano 20133, Italy.
This work provides a mathematical derivation of a quasi-stationary (QS) model for multimode parametric down-conversion (PDC), which was presented in Gatti . (Gatti ., .
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Université Paris Cité, CNRS, Laboratoire Matériaux et Phénomènes Quantiques, 75013 Paris, France.
Harnessing high-dimensional entangled states of light presents a frontier for advancing quantum information technologies, from fundamental tests of quantum mechanics to enhanced computation and communication protocols. In this context, the spatial degree of freedom stands out as particularly suited for on-chip integration. But while traditional demonstrations produce and manipulate path-entangled states sequentially with discrete optical elements, continuously coupled nonlinear waveguide systems offer a promising alternative where photons can be generated and interfere along the entire propagation length, unveiling novel capabilities within a reduced footprint.
View Article and Find Full Text PDFAnal Chem
December 2024
Joint Mass Spectrometry Centre/Chair of Analytical Chemistry, University of Rostock, 18059 Rostock, Germany.
To our knowledge, this study presents the first implementation of wavelength-resolved resonance-enhanced multiphoton ionization (REMPI) spectroscopy under atmospheric pressure ionization conditions using a high-resolution mass spectrometric system. Atmospheric pressure laser ionization MS spectroscopic measurements were conducted on over 70 different polycyclic aromatic hydrocarbons (PAHs) and hetero-PAHs (N, S, and O) in standard solutions, as well as three complex PAH-containing samples. The results demonstrate the successful transfer of REMPI spectroscopy from vacuum to atmospheric pressure conditions, maintaining spectral integrity without significant band broadening.
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