Objective: The main objective of this study was to analyze the clinical behavior and the impact of nodal metastasis on the prognosis of upper alveolus squamous cell carcinoma (SCC).
Materials And Methods: The medical records of 110 patients with SCC of the upper alveolus (International Classification of Diseases-10-C03.0) diagnosed during 2010-2015 were reviewed. Survival analysis was done using the Kaplan-Meier method and was compared using log rank-test. < 0.05 was considered statistically significant.
Results: Of the 110 patients, 59 were males and 51 were females. Forty-six (41.8%) patients presented with lymph node metastasis. Fifty-three (51.8%) patients presented in Stage IVA, thirty (27.3%) patients in Stage IVB, ten (9.1%) patients in Stage III, 12 (10.9%) patients in Stage II. The 5-year overall survival (OS) was 71.1% in Stage II, in Stage III it was 65.6%, in Stage it was IVA 56.7%, and in Stage IVB it was 19.4% ( = 0.02). The 5-year OS for node negative compared with node positive was 66.3% versus 37.3%, respectively ( = 0.019).
Conclusion: Presence of lymph node metastasis is associated with lower survival rates. Adequate surgical resection with adjuvant treatment, where necessary, offers the best chance of disease control.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348776 | PMC |
| http://dx.doi.org/10.4103/sajc.sajc_66_18 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of porcine collagen matrix versus rotated pedicle palatal connective tissue flap on the soft-tissue closure after the immediate posterior implantation: study protocol for a randomised controlled trial.
BMJ Open
January 2025
Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China
Introduction: Soft-tissue defect is commonly seen in immediate maxillary posterior implantation because of tooth extraction wound and tension from bone graft. Bone graft materials exposure has a significant detrimental influence on bone augmentation. However, previous studies lack sufficient evidence to guide wound closure after immediate posterior implantation.
View Article and Find Full Text PDFSocket preservation following tooth extraction: an experimental study comparing β-Tricalcium phosphate and F18 bioglass in rats.
Oral Maxillofac Surg
December 2024
Department of Basic and Oral Biology, Ribeirão Preto School of Dentistry, University of São Paulo, Via do Café s/n, Ribeirão Preto, 14040-900, SP, Brazil.
Purpose: To evaluate the efficacy of two third-generation resorbable biomaterials-F18 bioglass and β-tricalcium phosphate (β-TCP)-in promoting new bone formation in post-extraction sockets in rats. β-TCP, a synthetic porous ceramic, is well-established in clinical use, while F18 bioglass, a novel silica based bioglass.
Methods: After extraction of the right upper incisor of 45 rats, the sockets were filled either with F18 or β-TCP, or left to naturally fill with a blood clot in control group.
Maxilla of Siamopithecus eocaenus (Anthropoidea, Primates) from the Paleogene of Krabi, Thailand, and its taxonomic status.
J Hum Evol
January 2025
Laboratory Paleontology, Evolution, Paleoecosystems and Paleoprimatology (PALEVOPRIM), UMR 7262 CNRS, University of Poitiers, France.
Detailed descriptions of the maxillae of Siamopithecus eocaenus, discovered from the latest Eocene/earliest Oligocene lignite mine in the Krabi basin of Peninsular Thailand, are presented. They include the morphology of P-M, the palate, a partial orbital region, and the zygomatic root. The specimen exhibits distinctive dental features including a single-rooted P alveolus, a protocone on the P and P, and a true hypocone on the upper molars, indicating its derived anthropoid dentition.
View Article and Find Full Text PDFEffect of Local Zoledronic Acid Application in Alveolar Bone Healing: An Experimental Study.
J Craniofac Surg
October 2024
Department of Stomatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences.
Article Synopsis
- This study investigated how applying Zoledronic Acid (ZA) with a collagen sponge affects the healing of tooth extraction sites in rabbits over 4, 8, and 12 weeks.
- Results showed that the ZA group had significantly higher bone density compared to the group that only received the collagen sponge, especially at 8 and 12 weeks.
- While there was no noticeable difference in ridge height and width between the two groups, the ZA group showed a higher volume of collagen and fewer indicators of bone resorption, suggesting better quality of the new bone formed.
Utility of Orthodontic Braces as Flexible Splint for Stabilizing an Avulsed Tooth: A Case Report.
Case Rep Dent
September 2024
Dentistry Deparment Kings Dental Center, Al Khor, Qatar.
Dental avulsion is a traumatic dental injury with complete displacement of the tooth outside the bony socket. Both primary and permanent teeth are predisposed to such traumatic incidents. The most effective treatment in such cases is tooth replantation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!