Patients with vitamin C deficiencies and parkinsonism can show rapid improvement with vitamin C replacement therapy.
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Nutrients
December 2024
Department of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, Turkey.
The brain contains many interconnected and complex cellular and molecular mechanisms. Injury to the brain causes permanent dysfunctions in these mechanisms. So, it continues to be an area where surgical intervention cannot be performed except for the removal of tumors and the repair of some aneurysms.
View Article and Find Full Text PDFFront Hum Neurosci
November 2024
Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: The status of vitamin D has been proposed to have an impact on cognition. Gray matter volume (GMV) is a potential marker of cognitive function. We investigated whether lower serum 25-hydroxyvitamin D level was associated with reduced cerebral GMV in Parkinson's disease with non-dementia (PDND) patients.
View Article and Find Full Text PDFCureus
November 2024
Department of Internal Medicine, South County Hospital, Warwick, USA.
Seborrheic dermatitis (SD), a chronic inflammatory skin condition consisting of itchy, red patches with greasy scales, has been linked to numerous systemic conditions. This review evaluates comorbidities and lifestyle factors that are associated with seborrheic dermatitis. A literary search was conducted in August 2024 using EMBASE, PubMed, and Medline Industries, and evaluated according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
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November 2024
Department of Neurology, Shenzhen People's Hospital, The First Affiliated Hospital, Southern University of Science and Technology, The Second Clinical Medical College, Jinan University, Shenzhen, China.
Background: Higher intake of antioxidants is associated with reduced risk of various chronic diseases. However, the relationship between composite dietary antioxidants and frailty has not been characterized, especially in neurodegenerative conditions like Parkinson's disease (PD) where frailty is highly prevalent. This study aimed to investigate the association between composite dietary antioxidant index (CDAI), a composite score reflecting antioxidant vitamin and mineral intakes, and frailty risk in the general United States (US) population and PD patients.
View Article and Find Full Text PDFMetab Brain Dis
December 2024
Research Laboratory, Molecular Bases of Human Pathology, Faculty of Medicine, University of Sfax, Sfax, LR19ES13, Tunisia.
Multiple sclerosis (MS) can induce cardiac autonomic dysfunction identified by a decreased heart rate variability (HRV) which was linked to oxidative stress, vitamin D deficiency and sleep disturbance. Previous MS studies revealed the antioxidant and anti-inflammatory effects of exogenous melatonin, as well as its benefits on sleep and vitamin D. We aimed to investigate the change in HRV, oxidative stress, systemic inflammation and sleep following melatonin supplementation in MS patients.
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