Laser therapy is becoming common place in veterinary medicine with little evidence proving efficacy or dosages. This study evaluated surgical wound healing in canines. Twelve Dachshunds underwent thoraco-lumbar hemilaminectomies for intervertebral disc disease (IVDD). Digital photographs were taken of their incisions within 24 h of surgery and 1, 3, 5, 7, and 21 days postoperatively. The first three dogs were used to create a standardized scar scale to score the other dogs' incision healing. The remaining 9 dogs were randomly assigned to either receive 8 J/cm laser therapy once a day for 7 days or the non-laser treated control group. Incision healing was scored based on the scar scale from 0 to 5, with zero being a fresh incision and five being completely healed with scar contraction and hair growth. All scar scores significantly improved with increasing time from surgery (<0.001). Good agreement was achieved for inter-rater reliability ( = 0.9). Laser therapy increased the scar scale score, showed improved cosmetic healing, by day seven and continued to be significantly increased on day 21 compared to control dogs ( < 0.001). Daily application of laser therapy at 8J/cm2 hastened wound healing in Dachshunds that received thoracolumbar hemilaminectomies for IVDD. It also improved the cosmetic appearance.
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http://dx.doi.org/10.3389/fvets.2018.00349 | DOI Listing |
Laryngoscope
January 2025
Department of Otolaryngology-Head and Neck Surgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, U.S.A.
Objective: To identify the most effective treatment modality for achieving favorable outcomes in early glottic tumors with anterior commissure involvement (ACI).
Data Sources: PubMed, Embase, Web of Science, and ScienceDirect.
Review Methods: Random-effects proportional meta-analysis model is used to evaluate the oncological and functional outcomes of transoral laser microsurgery (TLM) versus radiation therapy (RT) in early glottic (T1-T2) cancer with ACI.
J Clin Med
January 2025
2nd Chair and Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Genitourinary Syndrome of Menopause (GSM) is a prevalent condition in postmenopausal women characterized by symptoms such as vaginal dryness, itching, and urinary tract issues due to declining estrogen levels. Despite its widespread impact on quality of life, GSM often remains underdiagnosed and without effective treatment. This study assessed the long-term efficacy of fractional CO laser treatment in alleviating GSM symptoms in perimenopausal women.
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Department of Internal Medicine, Angiology and Physical Medicine, Center for Laser Diagnostics and Therapy, Medical University of Silesia in Katowice, Batorego 15 Street, 41-902 Bytom, Poland.
Inflammatory bowel disease (IBD) is an immune disorder of the gastrointestinal tract with a complex aetiopathogenesis, whose development is influenced by many factors. The prevalence of IBD is increasing worldwide, in both industrialized and developing countries, making IBD a global health problem that seriously affects quality of life. In 2019, there were approximately 4.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Laboratory for Functional and Metabolic Imaging (LIFMET), Institute of Physics, Swiss Federal Institute of Technology (EPFL), Station 3, 1015 Lausanne, Switzerland.
Photobiomodulation (PBM) therapy, a therapeutic approach utilizing low-level light, has garnered significant attention for its potential to modulate various biological processes. This study aimed at optimizing and investigating the effects of PBM on angiogenesis and mitochondrial metabolic activity. In vitro experiments using human umbilical vein endothelial cells (HUVECs) and vascular smooth muscle cells (VSMCs) were performed to assess PBM's impacts on cell migration, proliferation, endogenous protoporphyrin IX production, mitochondrial membrane potential, Rhodamine 123 fluorescence lifetime, mitochondrial morphology, and oxygen consumption.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Engineering and Technology of Chemical Processes, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Due to the high mortality rate of ovarian cancer, there is a need to find novel strategies to improve current treatment modalities. Natural compounds offer great potential in this field but also require the careful design of systems for their delivery to cancer cells. Our study explored the anticancer effects of novel resveratrol (RSV)- and curcumin (CUR)-loaded core-shell nanoparticles in human ovarian cancer cells.
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