Posterior reversible encephalopathy syndrome due to hypercalcaemia: a rare cause.

BMJ Case Rep

Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Published: February 2019

Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological entity described by Hinchey in late 90's, characterised by variable associations of seizure activity, consciousness impairment ranging from confusion to coma, headaches, visual abnormalities, nausea/vomiting and focal neurological signs. Common causes are accelerated hypertension, eclampsia, preeclampsia, cytotoxic drug use and autoimmune diseases like systemic lupus erythematosus.We report a case of PRES in a 62-year-old female patient due to hypercalcemia secondary to vitamin D toxicity on treatment with calcium supplements and vitamin D for secondary hypoparathyroidism. She had seizures and visual defects on presentation which recovered completely with treatment of hypercalcemia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381982PMC
http://dx.doi.org/10.1136/bcr-2017-223415DOI Listing

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