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VEGFR3 mitigates hypertensive nephropathy by enhancing mitophagy via regulating crotonylation of HSPA1L.
Cell Commun Signal
January 2025
Department of Cardiology, the 2nd Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Oxidative stress-associated proximal tubular cells (PTCs) damage is an important pathogenesis of hypertensive renal injury. We previously reported the protective effect of VEGFR3 in salt-sensitive hypertension. However, the specific mechanism underlying the role of VEGFR3 in kidney during the overactivation of the renin-angiotensin-aldosterone system remains unclear.
View Article and Find Full Text PDFPrognosis after one- and two-stage revision surgery for periprosthetic joint infection: A systematic review and meta-analysis.
J Orthop Surg (Hong Kong)
January 2025
Sports Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Objective: Revision surgeries for periprosthetic joint infections (PJIs) in arthroplasty can follow either one- or two-stage treatment protocols. Previous studies have reported similar reinfection rates and reductions in complication rates for both treatment options. However, the literature on the selection of one protocol is still controversial.
View Article and Find Full Text PDFIntroduction: The aim of this study was to define the relationships between factors other than transferrin saturation (TS) to mean corpuscular volume (MCV) and macrocytosis (MCV > 100 fL) in p.C282Y (rs1800562) homozygotes.
Methods: We studied white post-screening participants with p.
miR-208a-3p discriminates osteoporosis, predicts fracture, and regulates osteoclast activation through targeting STC1.
J Orthop Surg Res
January 2025
Department of Rehabilitation, The Affiliated Hospital of Youjiang Medical University for Nationalities, No.18, Zhongshan 2nd Road, Baise, 533000, Guangxi Zhuang Autonomous Region, China.
Background: Osteoporosis (OP) frequently occurs in post-menopausal women, increasing the risk of fracture. Early screening OP could improve the prevention of fractures.This study focused on the significance of miR-208a-3p in diagnosing OP and development regulation, aiming to explore a novel biomarker and therapeutic target for OP.
View Article and Find Full Text PDFComparative study of Baduanjin and brisk walking on balance and stability in older adults.
Exp Gerontol
January 2025
Graduate School of Shandong Sport University, Jinan 250102, Shandong, PR China.
Objective: To investigate the impact of practicing the health Qigong-Baduanjin exercise on lower limb balance among elderly individuals.
Methods: Two intervention methods, Baduanjin and brisk walking, were applied to study the effect of exercise on senior balancing. Sixty elderly individuals aged 65 to 79 were selected and randomly divided into the Baduanjin group, the brisk walking group, and the control group that did not engage in exercise.
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