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Interconnecting surgical science, art, philosophy and technology for holistic health.
J Ayurveda Integr Med
January 2025
Foundation for Ancient Indian Philosophy and Medicine, At 202, C.L.Magic, Prathamesh Coperative Housing society, Kondhwa Bk., Pune, 411048, Maharashtra, India. Electronic address:
Surgery is the branch of medicine which involves correction of the diseases by means of interventions and by means of various instruments and methods. Surgery in latin is called as Chirugi and in the Indian context it is termed as 'Shalyatantra'. Surgery is the science as well as the tantra or technology.
View Article and Find Full Text PDFLong COVID and gut microbiome: insights into pathogenesis and therapeutics.
Gut Microbes
December 2025
Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Post-acute coronavirus disease 2019 syndrome (PACS), following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (COVID-19), is typically characterized by long-term debilitating symptoms affecting multiple organs and systems. Unfortunately, there is currently a lack of effective treatment strategies. Altered gut microbiome has been proposed as one of the plausible mechanisms involved in the pathogenesis of PACS; extensive studies have emerged to bridge the gap between the persistent symptoms and the dysbiosis of gut microbiome.
View Article and Find Full Text PDFSymptoms in Persons With Either Active or Inactive Crohn's Disease Are Agnostic to Disease Phenotype: The Magic in Imagine Study.
J Clin Gastroenterol
January 2025
Department of Medicine, McMaster University, Hamilton, ON, Canada.
Background: We aimed to examine the relationship between disease symptoms and disease phenotype in a large Canadian cohort of persons with Crohn's disease (CD).
Methods: Adults (n=1515) with CD from 14 Canadian centers participated in the Mind And Gut Interactions Cohort (MAGIC) between 2018 and 2023. Disease activity was measured using the 24-item IBD Symptom Inventory-Short-Form (IBDSI-SF).
Involving national stakeholders in a systems approach to map drivers of childhood obesity and actions to prevent childhood obesity in Denmark: the Generation Healthy Kids Study.
Health Res Policy Syst
January 2025
Center for Clinical Research and Prevention, Health Promotion and Prevention, Frederiksberg Hospital, Frederiksberg, Denmark.
Background: Childhood obesity is a preventable global public health challenge, increasingly recognized as a complex problem, stemming from complex drivers. Obesity is characterized by multiple interdependencies and diverse influences at different societal levels. Tackling childhood obesity calls for a holistic approach that engages with complexity and recognizes that there is no single "magic bullet" intervention to prevent obesity.
View Article and Find Full Text PDFRecombinant production platform for Group A Streptococcus glycoconjugate vaccines.
NPJ Vaccines
January 2025
Division of Molecular Microbiology, School of Life Sciences, Dundee, United Kingdom.
Group A Streptococcus (Strep A) is a human-exclusive bacterial pathogen killing annually more than 500,000 patients, and no current licensed vaccine exists. Strep A bacteria are highly diverse, but all produce an essential, abundant, and conserved surface carbohydrate, the Group A Carbohydrate, which contains a rhamnose polysaccharide (RhaPS) backbone. RhaPS is a validated universal vaccine candidate in a glycoconjugate prepared by chemical conjugation of the native carbohydrate to a carrier protein.
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