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Endoscopic management to different isolated sphenoid fungal pathologies: case series of a tertiary hospital.
J Surg Case Rep
January 2025
Department of Otolaryngology-Head and Neck Surgery, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Isolated sphenoid sinus disease (ISSD) is a rare condition that accounts for roughly 3% of all sinusitis cases. ISSD is predominantly caused by infectious and inflammation processes, with underlying fungal pathologies. This case series aims to illustrate the endonasal endoscopic management of different isolated sphenoid fungal pathologies.
View Article and Find Full Text PDFSurgeon oriented reporting template for magnetic resonance imaging and endoanal ultrasound of anal fistulas enhances surgical decision-making.
World J Radiol
December 2024
Department of Ultrasound, First Affiliated Hospital, Hainan Medical University, Haikou 570102, Hainan Province, China.
In this editorial, a commentary on the article by Sudoł-Szopińska has been provided. Successful treatment of anal fistula (AF) relies on accurate diagnosis. Magnetic resonance imaging (MRI) and endoanal ultrasound (EUS) are important for the AF diagnosis.
View Article and Find Full Text PDFComparative Analysis of Acquired Resistance to Bortezomib in Prostate Cancer Cells Using Proteomic and Bioinformatic Tools.
J Cell Mol Med
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Department of Medical Biology, Faculty of Medicine, Kutahya Health Sciences University, Kutahya, Turkey.
Chemotherapy is a potent tool against cancer, but drug resistance remains a major obstacle. To combat this, understanding the molecular mechanisms behind resistance in cancer cells and the protein expression changes driving these mechanisms is crucial. Targeting the Ubiquitin-Proteasome System (UPS) has proven effective in treating multiple myeloma and shows promise for solid tumours.
View Article and Find Full Text PDFExperiences of tongue tie when breastfeeding twins: A qualitative study.
Midwifery
January 2025
School of Health, Education, Policing and Sciences, University of Staffordshire, UK.
Problem: Tongue tie is an added complication when breastfeeding, but little is known about the role tongue tie might play when breastfeeding twins.
Background: Twins are much less likely to be breastfed than singleton babies due to added complications regarding pregnancy, birth and ongoing care. Tongue tie can cause breastfeeding barriers including poor latch, inefficient milk transfer and nipple pain.
Measurement, decomposition and level-switching in historical science: Geochronology and the ontology of scientific methods.
Stud Hist Philos Sci
January 2025
Department of Philosophy, University of Pennsylvania, United States. Electronic address:
Philosophers of the historical sciences have focused to a significant extent on the problem of epistemic access facing these sciences: how do historical scientists overcome the relative scarcity of data about the past, compared to the present? Solving this problem usually requires solving another one, which I call the 'problem of ontic access:' how do historical scientists get access to entities and processes with properties that are potentially informative about the past? The case of geochronology illustrates one solution to this problem: historical scientists can get access to entities and processes with properties that are potentially informative about the past by exploiting the metaphysical structure of their domain. Geochronology experienced a spectacular explosion of its research boundaries in the 20th century. I explain this productivity by analyzing the ontology implicit in geochronological techniques.
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