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Effects of ethylenediaminetetraacetic acid chelation for calcific band keratopathy on corneal topography assessed by fourier harmonic analysis.
Jpn J Ophthalmol
January 2025
Department of Ophthalmology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Purpose: Chemical chelation with ethylenediaminetetraacetic acid (EDTA) is an established treatment for calcific band keratopathy (CBK), whereas removal of calcium deposits from the subepithelial layer of the cornea may cause corneal irregularity. Using Fourier harmonic analysis, we analyzed the corneal topography in eyes with CBK treated by EDTA chelation.
Study Design: Retrospective, single-center study.
Measuring the effects of motion corruption in fetal fMRI.
Hum Brain Mapp
February 2025
Computational Imaging Research Lab, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Irregular and unpredictable fetal movement is the most common cause of artifacts in in utero functional magnetic resonance imaging (fMRI), affecting analysis and limiting our understanding of early functional brain development. The accurate detection of corrupted functional connectivity (FC) resulting from motion artifacts or preprocessing, instead of neural activity, is a prerequisite for reliable and valid analysis of FC and early brain development. Approaches to address this problem in adult data are of limited utility in fetal fMRI.
View Article and Find Full Text PDFTherapeutic insight into the role of nuclear protein HNF4α in liver carcinogenesis.
Adv Protein Chem Struct Biol
January 2025
Department of Bio-Medical Sciences, School of Bio Sciences and Technology, Vellore Institute of Technology (VIT), Vellore, Tamil Nadu, India. Electronic address:
Hepatocyte nuclear factor 4-alpha (HNF4α), a well-preserved member of the nuclear receptor superfamily of transcription factors, is found in the liver. It is recognized as a central controller of gene expression specific to the liver and plays a key role in preserving the liver's homeostasis. Irregular expression of HNF4α is increasingly recognized as a crucial factor in the proliferation, cell death, invasiveness, loss of specialized functions, and metastasis of cancer cells.
View Article and Find Full Text PDFPseudoprecocious puberty and gynaecomastia as presenting features of Peutz-Jeghers syndrome.
BMJ Case Rep
January 2025
Diabetes and Endocrinology, Children's Health Ireland at Crumlin, Dublin 12, Ireland.
A boy in mid-childhood presented with right-sided gynaecomastia, which was excised. He represented and, on review by endocrinology, Tanner staging showed stage 2 left-sided glandular breast tissue and some features of virilisation. His testicular volumes remained prepubertal (3 mL).
View Article and Find Full Text PDFFactors influencing forearm swelling after transradial artery intervention and establishment of a predictive model: a prospective study.
Eur J Cardiovasc Nurs
January 2025
Department of cardiovascular medicine, Peking University Third Hospital, 100080 Beijing, China.
Aims: Forearm swelling is a common complication following transradial artery interventions. Identifying the factors that influence this swelling and developing predictive models for it are crucial yet underexplored issues. This study was performed to investigate the risk factors for forearm swelling after transradial artery puncture and construct a predictive model.
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