Personalized Medicine and the Treatment of Hypertension.

Curr Hypertens Rep

Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, 5570C MSRB II, 1150 West Medical Center Drive, SPC 5678, Ann Arbor, MI, 48109-5678, USA.

Published: February 2019

AI Article Synopsis

  • The review focuses on how personalized medicine can impact the treatment of hypertension, especially resistant cases.
  • It introduces a framework for managing hypertension that balances simplicity and personalization, categorizing treatment strategies based on their information burden.
  • While standard treatments work well for most patients, those with unique hypertension types may benefit from a more tailored approach, prompting clinicians to stay updated on innovative personalized treatment options.

Article Abstract

Purpose Of Review: The purpose of this review is to discuss the implications of personalized medicine for the treatment of hypertension, including resistant hypertension.

Recent Findings: We suggest a framework for the personalized treatment of hypertension based on the concept of a trade-off between simplicity and personalization. This framework is based on treatment strategies classified as low, medium, or high information burden personalization approaches. The extent to which a higher information burden is justified depends on the clinical scenario, particularly the ease with which the blood pressure can be controlled. A one-size-fits-many treatment strategy for hypertension is efficacious for most people; however, a more personalized approach could be useful in patients with subtypes of hypertension that do not respond as expected to treatment. Clinicians seeing patients with unusual hypertension phenotypes should be familiar with emerging trends in personalized treatment of hypertension.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594382PMC
http://dx.doi.org/10.1007/s11906-019-0921-3DOI Listing

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